Sökning: "wound contraction"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden wound contraction.

1. 1. Connective tissue contraction in wound healing : An experimental study in vivo and in vitro

   Författare :M. Reza Ghassemifar; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Contraction of connective tissue is an important part of tissue repair that reduces the wound space and helps to decrease the formation of scar tissue, both of which are needed to restore tissue integrity. In the present study, certain cellular mechanisms that are active during connective tissue contraction were assessed and the influence of transforming growth factor-. LÄS MER

3. 2. Negative Pressure Wound Therapy - Effects on Sternotomy Wounds and the Intrathoracic Organs

   Författare :Christian Torbrand; Lund Oftalmologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NPWT; negative pressure; vacuum-assisted closure; sternotomy wounds; deep sternal wound infection; mediastinitis; thoracic surgery; pressure transduction; neurohormones; neuropeptides; total heart volume variation; cardiac output; wound contraction; macrodeformation;

   Sammanfattning : Negative pressure wound therapy (NPWT) has been widely adopted for the treatment of deep sternal wound infections due to its excellent clinical outcome. However, the mechanisms of action and effects on hemodynamics have not been thoroughly elucidated. LÄS MER

4. 3. Negative Pressure Wound Therapy. Therapy Settings and Biological Effects in Peripheral Wounds

   Författare :Ola Borgquist; Lund Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Negative pressure wound therapy; vacuum-assisted closure; wound healing;

   Sammanfattning : Negative pressure wound therapy (NPWT) promotes wound healing through several mechanisms, e.g., altered periwound blood flow, mechanical deformation of the wound edge tissue, and drainage of excess fluid and debris. LÄS MER

5. 4. Negative Pressure Wound Therapy - Mechanisms of Action and Protecting Exposed Blood Vessels in the Wound Bed

   Författare :Erik Anesäter; Thoraxkirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Negative pressure wound therapy; wounds; complications; experimental surgery; blood flow;

   Sammanfattning : NPWT has recently been associated with severe complications and bleeding when used in wounds with exposed blood vessels. The aims of this work were to investigate the mechanisms of action of NPWT and to explore the possibility of using thin plastic discs to protect exposed blood vessels in the wound bed during NPWT. LÄS MER

7. 5. The Roles of Growth Factor Interactions and Mechanical Tension in Angiogenesis

   Författare :Ludvig Petersson; Pär Gerwins; Filip Farnebo; Uppsala universitet; []
   Nyckelord :angiogenesis; myofibroblast; wound healing; VEGF; FGF; PDGF; endocan; endothelial cell; vascularization; MEDICINE; MEDICIN; Medicin; Medicine;

   Sammanfattning : Angiogenesis, the formation of new blood vessels from preexisting ones through creation of new vessel branch points by sprouting or vessel splitting, is an important part of tissue growth in both physiological processes like wound healing and pathological conditions such as cancer. Growth factors like VEGF-A, FGF-2 and PDGF-BB are involved in both types of angiogenesis. LÄS MER