Sökning: "withdrawal symptoms"

Visar resultat 21 - 25 av 41 avhandlingar innehållade orden withdrawal symptoms.

  1. 21. Vocally disruptive behaviour in severely demented patients in relation to institutional care provided

    Författare :Ingalill Rahm Hallberg; Astrid Norberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dementia; vocally disruptive behaviour; shouting; nursing care; sensory deprivation; understimulâtion; anxiety; object relation theory; caregivers1 reactions; E.H. Erikson1s theory;

    Sammanfattning : Thirty-seven patients identified as vocally disruptive and a control group, selected from 264 patients at psychogeriatric wards were studied. Tape-recordings of their vocal behaviour, ratings of their functional performance and symptoms related to dementia, observations of their behaviour, activities and interaction with caregivers were performed. LÄS MER

  3. 22. Impact of Pain and Evaluation of Education and Self-Care in Patients with Head and Neck Cancer

    Författare :Anne Söderlund Schaller; Britt Larsson; Gunilla Liedberg; Elena Dragioti; Britt-Marie Stålnacke; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : It is not unusual for patients with head and neck cancer (HNC) to suffer from both tumor and treatment-related pain that is difficult to alleviate despite individualized pharmacological treatment.The presence of concomitant various dimensions of pain in patients during the often difficult period following radiotherapy (RT) has not been elucidated. LÄS MER

  4. 23. The diagnostic challenge of Parkinsonian syndromes. Clinical and laboratory evaluation

    Författare :Björn Holmberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; MSA; PSP; autonomic tests; differential diagnosis; levodopa test; NFL; GFAP;

    Sammanfattning : Background: The differentiation between Parkinson's disease (PD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) may be difficult, but it is important for prognostic and therapeutic purposes. The aim of this study was to evaluate the differential diagnostic capacity of laboratory tests in a population of patients fulfilling strict clinical criteria for these disorders. LÄS MER

  5. 24. The analgesic mechanisms of buprenorphine

    Författare :Poli Francois Kouya; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Buprenorphine; morphine; cross-tolerance; g- opioid receptors; inbred mice.;

    Sammanfattning : Buprenorphine, a derivative of thebaine, is a semi-synthetic opiate and a partial p-opioid receptor agonist. Buprenorphine is also a weak kappa-opioid receptor antagonist. Buprenorphine is used clinically as an analgesic and for maintenance therapy of opiate-dependent subjects because it produces limited withdrawal symptoms. LÄS MER

  7. 25. Discovery of Small Peptides and Peptidomimetics Targeting the Substance P 1-7 Binding Site : Focus on Design, Synthesis, Structure-Activity Relationships and Drug-Like Properties

    Författare :Rebecca Fransson; Anja Sandström; John S Svendsen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; substance P 1-7; peptidomimetics; structure-activity relationship; drug-like properties; phenylalanine; imidazole; MAP aryl amides; carbonylation; Pharmaceutical chemistry; Farmaceutisk kemi; Medicinal Chemistry; Läkemedelskemi;

    Sammanfattning : Biologically active peptides are important for many physiological functions in the human body and therefore serve as interesting starting points in drug discovery processes. In this work the neuropeptide substance P 1–7 (SP1–7, H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-OH), which has been demonstrated to reduce neuropathic pain and attenuate opioid withdrawal symptoms in animal models, has been addressed in a medicinal chemistry program with the overall aim of transforming this bioactive peptide into more drug-like compounds. LÄS MER