Sökning: "wikner"

Visar resultat 1 - 5 av 42 avhandlingar innehållade ordet wikner.

  1. 1. Insights into enzymatic thiamin catalysis

    Författare :Christer Wikner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :thiamin; transketolase; catalysis; catalytic mechanism; site-directed muta genesis; enzyme kinetics; circular dichroism Christer Wikner; Molecular Structural Biology; Dept. of Medical Biochemistry and Biophysics; Karolinska Institutet; S-171 77 Stoc;

    Sammanfattning : Thiamin diphosphate, the biologically active form of vitamin B,, functions as a cofactor in various enzymes in the cell. The protein enhances the reactivity of the cofactor by binding it in a very specific manner. LÄS MER

  2. 2. Dynamic Modelling and Analysis of Information Flows in Production-Inventory and Supply Chain Systems

    Författare :Joakim Wikner; Jönköping University; []
    Nyckelord :Industrial dynamics; Control theory; Production-inventory system; Supply chain; Net present value; MCDM;

    Sammanfattning : System dynamics is the fundamental concept of this academic dissertation. The focus is on analysis and modelling of properties representative for production-inventory and supply chain systems. The modelling approach is based on Industrial Dynamics but employs a hybrid approach of Control Theory and simulation in the analysis. LÄS MER

  3. 3. Melatonin secretion and excretion : a clinical study focusing on factors and disease states which might influence melatonin

    Författare :Johan Wikner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Melatonin; ethanol; Wernicke-Korsakoff syndrome; calcium; calcium channel blocker; verapamil; 6-sulphatoxy-melatonin; Obstructive Sleep Apnea Syndrome; Continuos Positive Airway Pressure; Fibromyalgic syndrome; TSH; somatostatin; octreotide; GH; Hypothyroidism;

    Sammanfattning : The overall aim of this thesis was to find out whether other factors than the the light-dark changes influence the function of the pineal gland. Since melatonin (MT) itself, or its precursor serotonin, are of importance for sleep, mood, and pain perception, disease states - or situations in which these functions are disturbed - should be of interest to investigate in this context. LÄS MER

  4. 4. Predation on marine pelagic bacteria : On the in situ rates, regulation and dynamics of bacterivory studied with a molecular genetic technique

    Författare :Johan Wikner; Åke Hagström; Caron David; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Marine; grazing; minicells; molecular genetics; method; predation rate; dynamics; bacterivore; predator-prey; mikrobiologi; Microbiology;

    Sammanfattning : .... LÄS MER

  5. 5. Value co-creation as practice : On a supplier's capabilities in the value generation process

    Författare :Sarah Wikner; Ethel Brundin; Susanne ; Hertz; Björn Axelsson; Jönköping University; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Value co-creation; value-in-use; dynamic capabilities; supplier-customer relationships; Business studies; Företagsekonomi;

    Sammanfattning : How can suppliers contribute to their customers’ value creating processes? Although this question is crucial for firms’ collaboration with customers and for their competitiveness, it is not clear how firms co-create value with their customers. Research on value co-creation has increased notably the last years. LÄS MER