Sökning: "white matter hyperintensities"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden white matter hyperintensities.

  1. 1. The matter of white and gray matter in cognitive impairment

    Författare :Soheil Damangir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cognitive impairment spans from minor subjective cognitive impairment to disabling dementia. Many biomarkers have been developed to monitor different aspects of cognitive impairment. Magnetic resonance imaging is the most used neuroimaging biomarker in research and can measure gray matter (GM) and white matter (WM) changes. LÄS MER

  3. 2. Risk factors for development of neurocognitive disorders

    Författare :Anna-Märta Gustavsson; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular risk factors; dementia; Alzheimer’s disease; ß-amyloid; white matter hyperintensities; cerebral small vessel disease;

    Sammanfattning : Vascular risk factors are believed to be involved in dementia development by increasing risk of the most common dementia types, Alzheimer’s disease (AD) and vascular dementia. The aim of this thesis was to study if risk factors affect key brain pathology directly, by using biomarkers for dementia in preclinical stages, and to assess previous findings in a large population-based setting. LÄS MER

  4. 3. Fatigue after traumatic brain injury : exploring novel methods for diagnosis and treatment

    Författare :Nils Berginström; Anna Nordström; Peter Nordström; Lars Nyberg; Jan Lexell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; fatigue; OSU6162; randomized clinical trials; functional magnetic resonance imaging; neuropsychology; structural magnetic resonance imaging; white matter hyperintensities; rehabiliteringsmedicin; Rehabilitation Medicine;

    Sammanfattning : Background: Traumatic brain injury (TBI) is one of the most common causes of disability and mortality. While some patients recover quickly, especially at the mild side of the injury severity continuum, many will experience symptoms for years to come. LÄS MER

  5. 4. Clinical evaluation and implications of left atrial remodeling in atrial fibrillation : From silent cerebral lesions and atrial stunning to novel electrocardiographic tools for prediction of arrhythmia outcome

    Författare :Panagiotis Arvanitis; Carina Blomström-Lundqvist; Mårten Rosenqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; left atrial remodeling; recurrence; new-onset; silent cerebral lesions; white matter hyperintensities; cardioversion; pulmonary vein isolation; risk factors; electrocardiographic predictors; P-wave indices; machine learning; predictive models; Covid-19;

    Sammanfattning : Atrial fibrillation (AF) is the most common cardiac arrhythmia. Left atrial (LA) remodeling and reverse remodeling are associated with cerebral involvement and cognitive function (CF) changes. Risk stratification for AF related outcomes is essential in the management of patients with AF. LÄS MER

  7. 5. Applications of diffusion MRI: Tensor-valued encoding, time-dependent diffusion, and histological validation

    Författare :Jan Brabec; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diffusion MRI; meningioma; glioma; brain tumors; intracranial tumors; undulations; restricted diffusion; time dependence; spherical b-tensor encoding; linear b-tensor encoding; histogram analysis; anisotropic kurtosis; isotropic kurtosis; hyperintensity; conspicuity; white matter; detection; diffusion spectrum; consistency; type; grade; axon diameter; axonal trajectories; Fysicumarkivet A:2022:Brabec;

    Sammanfattning : Diffusion MRI (dMRI) sensitizes the MR signal to the diffusion of water molecules at the microscopic level and thereby non-invasively probes tissue microstructure. This is relevant when determining biological properties of tissues, for example, cancer type and its malignancy. LÄS MER