Sökning: "voltage-gated potassium channels"
Visar resultat 16 - 20 av 24 avhandlingar innehållade orden voltage-gated potassium channels.
16. Polyunsaturated Fatty Acids Modifying Ion Channel Voltage Gating
Sammanfattning : Voltage-gated ion channels play fundamental roles in neuronal excitability and therefore dysfunctional channels can cause disease. Epilepsy is such a disease, affecting about 1% of the population and being characterized by synchronous electric activity of large groups of neurons leading to various types of seizures. LÄS MER
17. Membrane Induced Structure in Transmembrane Signaling Proteins and Peptides : Peptide–Lipid Interactions Studied by Spectroscopic Methods
Sammanfattning : Biological membranes, defining the boundary of cells and eukaryotic organelles, are mainly composed of lipids and membrane proteins. Interactions between these lipids and proteins are needed to preserve the tight seal of the membrane, but also to induce structure for proper function in many membrane proteins. LÄS MER
18. NMR Investigations of Peptide-Membrane Interactions, Modulation of Peptide-Lipid Interaction as a Switch in Signaling across the Lipid Bilayer
Sammanfattning : The complexity of multi cellular organisms demands systems that facilitate communicationbetween cells. The neurons in our brains for instance are specialized in this cell-cellcommunication. LÄS MER
19. Biotransformation of the antineoplastic drug oxaliplatin : importance for effects and side effects
Sammanfattning : Oxaliplatin is a platinum-based cytostatic drug. It is used in combination with 5-fluorouracil and leucovorin for palliative and adjuvant treatment of metastatic colorectal cancer. LÄS MER
20. Detecting the dynamics of single biomolecules
Sammanfattning : This thesis is concerned with the detection of single biomolecules. Through detection of individual molecules it can be clarified whether a behavior which has been observed in a population is representative for all molecules. For detection confocal fluorescence microscopy was used, in particular Fluorescence Correlation Spectroscopy (FCS). LÄS MER