Sökning: "voltage-gated calcium channels"
Visar resultat 1 - 5 av 26 avhandlingar innehållade orden voltage-gated calcium channels.
1. Targeting the voltage-gated calcium channels as treatment for type 2 diabetes
Sammanfattning : L-type voltage-gated Ca2+ channels are expressed in the plasma membrane of muscles, neurons and endocrine cells where they serve as conductors of signals regulating cellular responses to changes in environment. Malfunctions of channels, as well as deregulations of their activity underlie numerous disorders and diseases commonly called channelopathies. LÄS MER
2. New aspects of voltage-gated calcium channel regulation in pancreatic beta-cells - Relevance for insulin release and type 2 diabetes
Sammanfattning : Voltage-gated Ca2+ channels are essential transducers of cellular signals in many electrically excitable cells. In the pancreatic beta-cell they mediate controlled Ca2+ influx, which is the final trigger for Ca2+ dependent release (exocytosis) of the blood glucose lowering hormone insulin. LÄS MER
3. Calcium transport in the Pacific oyster, Crassostrea gigas - in a changing environment
Sammanfattning : Pacific oyster, Crassostrea gigas, is globally one of the most important farmed bivalve species. A prominent features of the C. gigas is the thick CaCO3 shell covering the body of the animal and protecting it from the environment. LÄS MER
4. Site and Mechanism of Action of Resin Acids on Voltage-Gated Ion Channels
Sammanfattning : Voltage-gated ion channels are pore-forming membrane proteins that open or close their gates when the voltage across the membrane is changed. They underlie the electrical activity that enables the heart to pump blood and the brain to receive and send signals. LÄS MER
5. The Best Leading Role for Maintaining Normal β-cell Function Goes to MafA and Voltage-gated Calcium Channel Subunit γ4
Sammanfattning : .... LÄS MER