Sökning: "voltage sensor"
Visar resultat 1 - 5 av 80 avhandlingar innehållade orden voltage sensor.
1. Dynamics of the voltage-sensor domain in voltage-gated ion channels : Studies on helical content and hydrophobic barriers within voltage-sensor domains
Sammanfattning : Voltage-gated ion channels play fundamental roles in neural excitability and thus dysfunctional channels can cause disease. Understanding how the voltage-sensor of these channels activate and inactivate could potentially be useful in future drug design of compounds targeting neuronal excitability. LÄS MER
2. Voltage sensor activation and modulation in ion channels
Sammanfattning : Voltage-gated ion channels play fundamental roles in neural excitability, they are for instance responsible for every single heart beat in our bodies, and dysfunctional channels cause disease that can be even lethal. Understanding how the voltage sensor of these channels function is critical for drug design of compounds targeting neuronal excitability. LÄS MER
3. Molecular aspects on voltage-sensor movement
Sammanfattning : Voltage-gated ion channels are fundamental for electrical signaling in living cells. They are composed of four subunits, each holding six transmembrane helices, S1-S6. Each subunit contains a voltage-sensor domain, S1-S4, and a pore domain, S5-S6. LÄS MER
4. Voltage-Sensor Domains of Ion Channels : Physiology, Regulation, and Role in Disease
Sammanfattning : Brain function depends on the ability of neurons to sense and respond to electricity, which is mediated by small modules in the neuronal membrane called voltage-sensor domains (VSDs). Disruption of VSD function can cause neurological disease such as epilepsy. LÄS MER
5. High Voltage Insulation Diagnostics Utilizing HTS-SQUID Based Amplifiers
Sammanfattning : In the design and development of high voltage insulation systems, different diagnostic methods are often used for system characterization. It is therefore crucial to continuously improve existing methods and to develop new ones. LÄS MER