Sökning: "vitamin D analogues"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden vitamin D analogues.
1. Vitamin D Hydroxylating Enzymes and Analogues in Parathyroid Tumors and Breast Cancer
Sammanfattning : In hyperparathyroidism (HPT) raised serum concentrations of ionized calcium is caused by increased secretion of parathyroid hormone (PTH) by parathyroid tumors. Active vitamin D, 1α,25-dihydroxyvitamin D3, is known to suppress PTH secretion and to reduce proliferation of parathyroid tumor cells. LÄS MER
2. Vitamin D and Vitamin D-binding Protein in Psoriasis and Effects of Treatment
Sammanfattning : Background: Topical vitamin D analogues constitute an established treatment for psoriasis but the role of vitamin D in the pathogenesis of the disease remains controversial. The in loco production and immunomodulatory effects of vitamin D need to be elucidated. LÄS MER
3. Molecular mechanism of cell regulatory properties of vitamin D analogues in human cancer cell lines
Sammanfattning : The active form of vitamin D, 1α,25-dihydroxyvitamin D3, is a potent modulator of the induction of differentiation and inhibition of cell growth in both malignant and normal cells. Vitamin D and its analogues exert their effects through a transcription factor, the nuclear vitamin D receptor (VDR). LÄS MER
4. Expression and regulation of steroid metabolizing enzymes in cells of the nervous and skeletal systems : Special focus on vitamin D metabolism
Sammanfattning : Little is known about the mechanisms of vitamin D actions in the brain and bone. In this study, the metabolism of vitamin D and its regulation in various cell cultures of the nervous and skeletal systems were examined. LÄS MER
5. The human antimicrobial protein hCAP18/LL37 in wound healing and cell proliferation
Sammanfattning : Epithelia constitute the principal barriers separating the host and the potentially injurious environment, and defence of this interface is therefore essential. Antimicrobial peptides are key effector molecules of the innate immune system. LÄS MER