Sökning: "virus-like particles VLPs"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden virus-like particles VLPs.

  1. 1. Uukuniemi virus-like particles : a model system for bunyaviral assembly

    Författare :Anna K Överby; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Viruses are intracellular parasites that are unable to multiply except when inside a living cell of a host. Outside their host they remain inert. LÄS MER

  3. 2. Vaccination against Her2/neu : expressing cancer using chimeric virus-like particles

    Författare :Kalle Andreasson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Thanks to the development of vaccines, children are these days protected against infectious diseases like polio, diphtheria and tetanus simply by receiving a few injections. Imagine a scenario where these injections would also result in protection against cancer. LÄS MER

  4. 3. Studies on polyomavirus virus-like particles : as vaccines and vectors for immune and gene therapy

    Författare :Karin Tegerstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Polyomavirus; virus-like particles; immunotherapy; Her2 and dendritic cells;

    Sammanfattning : Virus-like particles (VLPs) are similar to natural virus particles except that they lack viral genes. They have a similar cellular uptake to the natural virus from which they are derived but are non-infectious and can therefore not reproduce themselves. LÄS MER

  5. 4. Murine polyomavirus VP1 virus-like particles as vectors for gene therapy and as vaccines against polyomavirus infection and tumors

    Författare :Andrea Vlastos Franzén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Polyomavirus; virus-like particles; pseudocapsids; gene therapy; vaccines; tumors;

    Sammanfattning : Murine polyomavirus (MPyV) is a double stranded DNA virus ubiquitous in mice. The virus genome encodes for three transforming antigens that interact with the host cell machinery in order to initiate viral production. The transforming antigens can under certain circumstances when not controlled, e.g. LÄS MER

  7. 5. Human Papillomavirus vaccination: Immunological and epidemiological studies

    Författare :Janka Ryding; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzyme-linked immunosorbent assay ELISA ; Human Papillomavirus HPV ; parallel line method PLL ; mathematical modeling; virus-like particles VLPs ; prevalence; serology;

    Sammanfattning : This thesis has evaluated the immunological- and epidemiological aspects of human papillomavirus transmission dynamics and its effect on circumcision. Effective prophylactic vaccines are based on type-specific neutralizing antibodies. A major neutralizing epitope is defined by the monoclonal antibody H16.V5. LÄS MER