Sökning: "virus-like particle"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden virus-like particle.

  1. 1. Uukuniemi virus-like particles : a model system for bunyaviral assembly

    Författare :Anna K Överby; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Viruses are intracellular parasites that are unable to multiply except when inside a living cell of a host. Outside their host they remain inert. LÄS MER

  3. 2. Norovirus, causative agent of winter vomiting disease, exploits several histo-blood group glycans for adhesion

    Författare :Gustaf E Rydell; Göteborgs universitet; []
    Nyckelord :norovirus; glycobiology; virus-like particle; FUT2; ABO H histo-blood group antigen; sialyl Lewis x; neoglycoprotein; glycosphingolipid; QCM-D; supported lipid bilayer;

    Sammanfattning : Norovirus is recognized as the major cause of outbreaks of gastroenteritis world-wide, yet no vaccines or drugs are available for prevention or treatment of the virus infection. Challenge studies and binding studies using virus-like particles (VLPs) have suggested susceptibility to norovirus infection to be associated with secretor status. LÄS MER

  4. 3. Protein adaptability involved in self-assembled icosahedral capsids

    Författare :Josefina Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :BK virus; lumazine synthase; virus-like particle; electron cryomicroscopy; quasiequivalence; assembly;

    Sammanfattning : Interactions between viral coat proteins determine the size and shape of the virus capsid. Therefore, the plain closed shell of a spherical virus provides an excellent resource for studying and testing protein-protein interactions so as to reveal the properties that lead to symmetrical capsids or other shapes. LÄS MER

  5. 4. Structural Studies of Bacteriophage PRR1 and HIV-1 protease

    Författare :Magnus Persson; Lars Liljas; Kaspars Tars; Félix Rey; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PRR1; HIV; Structural Biology; X-ray crystallography; PRR1; HIV-1 protease; NCS; crystallography; inhibitor; virus; bacteriophage; X-ray crystallography; Virology; Virologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : Viruses are a diverse genera of organisms adapted to thrive in many different hosts from prokaryotic to eukaryotic.We present here the structure of bacteriophage PRR1 virus-like particle (VLP), belonging to Leviviridae family. Our structure reveals calcium ions in the VLP. LÄS MER

  7. 5. Biochemical and epidemiological characterization of serogroup C rotavirus

    Författare :Mikael Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rotaviruses are classified into seven serogroups (A-G) on the basis of antigenic and genetic properties. Group A rotavirus is the most common cause of diarrhea in infants and young children in both developing and developed countries. LÄS MER