Sökning: "virus-host protein interactions"

Visar resultat 6 - 10 av 19 avhandlingar innehållade orden virus-host protein interactions.

  1. 6. Dissection of virus-host cell interactions in the early response to infection

    Författare :Marc D Panas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Stress granules (SG) are dynamic RNA/protein assemblies in the cytoplasm of the cell, formed under conditions of oxidative stress, heat shock or viral infections. These stress conditions trigger a sudden translational arrest, leading to a rapid switch of translation from housekeeping genes to stress-related factors. LÄS MER

  3. 7. Characterizing important flavivirus-host interactions : Replication, assembly, restriction factors and vaccine development

    Författare :Pham Tue Hung Tran; Magnus Johansson; Wessam Melik; Naveed Asghar; Sören Andersson; Laurent Chatel-Chaix; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flaviviruses; virus-host cell interaction; lunapark; ESCRT; ALIX; CHMP4A; ISG15; TRIMs; replicon virus-like particles; vaccine;

    Sammanfattning : The genus Flavivirus (family Flaviviridae) consists of important zoonotic viruses that cause morbidity and mortality worldwide. These viruses are enveloped and have a positive-sense single-stranded RNA genome encoding a polyprotein. LÄS MER

  4. 8. Functional characterization of interactions between the flavivirus NS5 protein and PDZ proteins of the mammalian host

    Författare :Karin Ellencrona; Magnus Johansson; Andrew Davidson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus TBEV ; West-Nile virus WNV ; Dengue virus DENV ; flavivirus; PDZ domains; ZO-2; ZO-1; RIMS2; Scribble; Interferon; JAK-STAT signaling; PDZ array; virus-host protein interaction; Genetics; Genetik; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Flaviviruses are found all over the world and affect and infect millions of people every year. Flavivirus infection can lead to severe clinical outcomes resulting in neuronal damages e.g. Tick-borne encephalitis virus (TBEV), or severe hemorrhagic fevers e. LÄS MER

  5. 9. Borna disease virus and its hosts : studies on virus-host interactions and virus detection

    Författare :Jonas Johansson Wensman; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Borna disease virus (BDV) is an RNA-virus persistently infecting the central nervous system of, and thereby causing neurological disorders in, several animal species, possibly including humans. Although several aspects of BDV and its pathologies have been studied for more than 100 years, further elucidation of the epidemiology and pathogenesis, and the development of reliable detection methods,is needed. LÄS MER

  7. 10. Human herpesvirus 6A and 6B : assay validation, virus-host interaction and clinical relevance

    Författare :Elin Engdahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human herpesvirus (HHV)-6A and HHV-6B are two ubiquitous herpesviruses that after primary infection can stay latent in the host. The two viruses can reactivate from latency and cause secondary complications. Also, diseases like multiple sclerosis and epilepsy have been associated with HHV-6A and HHV-6B. LÄS MER