Sökning: "virus neutralization"

Visar resultat 11 - 15 av 43 avhandlingar innehållade orden virus neutralization.

  1. 11. Serological and molecular methods for surveillance of influenza A virus

    Författare :Sofie Wallerström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The natural reservoir for influenza A viruses is birds, and numerous outbreaks of highly pathogenic avian influenza viruses have been documented. There is a risk of novel subtypes originating from birds infecting humans, and the question of migratory birds as long-distance vectors for highly pathogenic avian influenza viruses has also been raised. LÄS MER

  3. 12. Oncolytic Adenovirus Therapy of Neuroendocrine Tumors

    Författare :Justyna Leja; Magnus Essand; Valeria Giandomenico; Akseli Hemminki; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adenovirus; virotherapy; oncolytic virus; neuroendocrine tumors; chromogranin A; somatostatin receptors; microRNA; novel biomarkers; Molecular biology; Molekylärbiologi; Oncology; Onkologi; Virology; Virologi; Tumour biology; Tumörbiologi; Medical Science; Medicinsk vetenskap; Oncology; Onkologi; Medical Virology; Medicinsk virologi; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Neuroendocrine tumors (NETs), originally described as carcinoids, represent a rare and heterogeneous group of neoplasms associated with intensive secretion of hormones, bioactive peptides and amines. Most of the patients are diagnosed at a late stage of disease, often with liver metastases. LÄS MER

  4. 13. Coreceptor usage and sensitivity to neutralization of HIV-1 and HIV-2

    Författare :Yu Shi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; HIV-2; pathogenesis; neutralization; coreceptor usage; envelop sequence; glycosylation; U87.CD4 cells; GHOST 3 cells; CCR5; CXCR4;

    Sammanfattning : The aim of this project was to study neutralization and coreceptor use in HIV-1 and HIV-2. The first step was to develop a simple and standardized assay for detection and quantification of HIV- 1 neutralizing activity in human sera. LÄS MER

  5. 14. Natural killer cells and antibody-mediated effects in human immunodeficiency virus infection

    Författare :Susanne Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The human immunodeficiency virus (HIV-1) effectively avoids immunologic eradication. Certain characteristics of the virus contribute to this, including the specific targeting of the body s own defense system, the ability to hide in the host cell genome and the vast viral variability. LÄS MER

  7. 15. Studies of hepatitis C virus envelope proteins : interaction with host cells and as targets for the humoral response

    Författare :Aster Beyene; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hepatitis C virus; Envelope protein 1 and 2 E1 and E2 ; humoral response; VSV pseudotype.;

    Sammanfattning : Hepatitis C virus (HCV) is a major cause of chronic hepatitis infection worldwide. It leads to chronic infection in over 80% in infected patients and may result in liver cirrhosis, hepatocellular carcinoma and autoimmune disorders. LÄS MER