Sökning: "viral"

Visar resultat 1 - 5 av 1029 avhandlingar innehållade ordet viral.

  1. 1. Bovine viral diarrhea virus : methods for purification of the virus and the viral subunits

    Författare :Per Kårsnäs; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  3. 2. HIV Persistence and Viral Reservoirs

    Författare :Arvid Edén; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; latency; cerebrospinal fluid; central nervous system; efavirenz; lopinavir; atazanavir; neopterin; viral decay;

    Sammanfattning : Although antiretroviral therapy (ART) can effectively inhibit replication of human immunodeficiency virus type 1 (HIV-1), the virus is able to persist in cellular and anatomical viral reservoirs. Latently infected resting memory CD4+ T-cells are an important cellular reservoir, and the central nervous system (CNS) an important anatomical reservoir for HIV-1 infection. LÄS MER

  4. 3. Evolution and viral mimicry of short linear motif-mediated interactions

    Författare :Filip Mihalič; Per Jemth; Leo James; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phage display; protein-protein interactions; large-scale discovery; short linear motifs; viral mimcry; viral hijacking; Biokemi; Biochemistry; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Proteins are one of the most fundamental building blocks of life and their interactions regulate every cellular process. Historically they have been conceptualized as predominantly folded entities with well-defined secondary and tertiary structures. LÄS MER

  5. 4. On gastrointestinal viral infections

    Författare :Thomas Beck-Friis; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; norovirus; rotavirus; SARS-CoV-2; gastroenteritis; diagnosis; elderly; epidemiology; humidity; COVID-19; genomic structural variation;

    Sammanfattning : Gastrointestinal viral infections cause considerable morbidity and mortality worldwide. Many factors influencing clinical presentation, disease severity, epidemiology, and transmission are not fully understood. LÄS MER

  7. 5. Interaction Characteristics of Viral Protease Targets and Inhibitors : Perspectives for drug discovery and development of model systems

    Författare :Cynthia F Shuman; Jordan J N Tang; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; viral proteases; biomolecular interactions; kinetics; thermodynamics; biosensors; drug discovery; Biokemi; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Sammanfattning : Viral proteases are important targets for anti-viral drugs. Discovery of protease inhibitors as anti-viral drugs is aided by an understanding of the interactions between viral protease and inhibitors. This thesis addresses the characterization of protease-inhibitor interactions for application to drug discovery and model system development. LÄS MER