Sökning: "viral replication"

Visar resultat 11 - 15 av 247 avhandlingar innehållade orden viral replication.

  1. 11. Functional Characterization of the Evolutionarily Conserved Adenoviral Proteins L4-22K and L4-33K

    Författare :Sara Östberg; Göran Akusjärvi; Stefan Schwartz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L4-22K; L4-33K; RNA; splicing; adenovirus; nuclear localization; replication; transcription; evolution; SR protein; MLP; promoter; E1A; serotypes;

    Sammanfattning : Regulation of adenoviral gene expression is a complex process directed by viral proteins controlling a multitude of different activities at distinct phases of the virus life cycle. This thesis discusses adenoviral regulation of transcription and splicing by two proteins expressed at the late phase: L4-22K and L4-33K. LÄS MER

  3. 12. Activation of Herpes simplex virus type 1 origin of DNA replication

    Författare :Alireza Aslani; Göteborgs universitet; []
    Nyckelord :DNA replication; Herpes simplex virus; helicase; UL9; OBP; ICP8; ATP; oriS; hairpin;

    Sammanfattning : Herpes simplex virus type 1 has been used to study the molecular mechanism of DNA replication. Initiation of DNA replication takes place at specific regions called origins of replication. The HSV-1 genome contains three origins of replication, one copy of oriL and two copies of oriS. LÄS MER

  4. 13. Protein interactions involved in viral replication characterized by T7 phage display

    Författare :Hamid Houshmand; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; protein-protein interaktion; fagdisplayteknik; HCV; polyomavirus; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Protein interactions are essential for many cellular processes. By utilizing protein-protein interactions, viruses can infect their host cells and replicate. Phage display can be used for identification and characterization of protein-protein interactions. LÄS MER

  5. 14. Herpes Simplex Virus 1 DNA replication and its role in recombination and transcription

    Författare :Ka-Wei Tang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Herpes Simplex Virus 1; DNA replication; DNA recombination; Transcription;

    Sammanfattning : Herpes simplex virus 1 (HSV-1) is one of nine different herpesvirus infecting man. They are all capable of establishing a life-long latent state following the primary infection. HSV-1 as well as other herpesviruses may reactivate from the latent state and give rise to a productive infection with clinical symptoms or asymptomatic shedding. LÄS MER

  7. 15. Viral Control of SR Protein Activity

    Författare :Camilla Estmer Nilsson; Neus Visa; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; ASF SF2; dephosphorylation; E4-ORF4; L1; MLTU; PP2A; splicing; SR proteins; vaccinia virus; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Viruses modulate biosynthetic machineries of the host cell for a rapid and efficient virus replication. One important way of modulating protein activity in eukaryotic cells is by reversible phosphorylation. In this thesis we have studied adenovirus and vaccinia virus, two DNA viruses with different replication stategies. LÄS MER