Sökning: "viral immunescape"

Hittade 1 avhandling innehållade orden viral immunescape.

1. 1. T-cell mediated control of Epstein-Barr virus infection : viral mechanisms of immune escape

   Författare :Jelena Vladmirovna Levitskaya; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Epstein-Barr virus; Cytotoxic T lymphocyte; CTL epitope; viral immunescape;

   Sammanfattning : Mechanisms regulating the immunogenicity of Epstein-Barr Virus (EBV)-encoded CTL peptide epitopes and their contribution to the escape of virus infected cells from CTL-mediated immunosurveillance were the subject of these studies. It was demonstrated that two HLA A11-restricted CTL epitopes of EBV nuclear antigen (EBNA)-4 (designated IVT and AVF) possessed different immunogenicity that appeared to be due to a rapid surface turnover of All molecules containing the AVF peptide. LÄS MER