Sökning: "viral entry"

Visar resultat 11 - 15 av 62 avhandlingar innehållade orden viral entry.

  1. 11. Altering HIV-1 envelope glycoprotein maturation and its effects on viral infectivity

    Författare :Alenka Jejcic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1;

    Sammanfattning : HIV-1 is dependent on its envelope glycoprotein (Env) to initiate infection. Env binds to cellular receptors and mediate the following fusion of the viral envelope with the cell plasma membrane. LÄS MER

  3. 12. Prevalance and prevention of sexually transmitted viral infections in the Bolivian Amazonas

    Författare :Marianela Patzi Churqui; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sexually transmitted infections; indigenous women; Bolivian Amazonas; medical plants; microbicides; cytokines; HSV-2; HPV; HBV;

    Sammanfattning : This thesis investigates the prevalence of sexually transmitted viral infections in women living in the Amazonas region of Bolivia and explores whether Bolivian medical plants can affect the immune system and prevent or treat infections with Herpes simplex virus type 2 (HSV-2) and inflammation. My PhD project was financed by the Swedish International Development Cooperation Agency (SIDA), and I did my work alternately in Bolivia and in Sweden. LÄS MER

  4. 13. Virus-host interactions : entry and replication of Crimean-Congo hemorrhagic fever virus

    Författare :Cecilia Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Crimean-Congo hemorrhagic fever (CCHF) is a severe acute human disease with potential lethal outcome caused by a virus, Crimean-Congo hemorrhagic fever virus (CCHFV). Not much is known regarding how CCHFV infects cells, replicates and why it cause vascular dysfunction. LÄS MER

  5. 14. Co-evolution of the HIV-1 R5 phenotype and the viral envelope glycoproteins

    Författare :Johanna Repits; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; envelope; R5; HIV-1; evolution;

    Sammanfattning : To gain entry into target cells, HIV-1 binds to CD4 via the viral glycoprotein gp120. This interac-tion initiates a series of events including binding of a coreceptor, CCR5 and/or CXCR4, and ulti-mately leads to gp41-mediated fusion of the viral and cell membranes. LÄS MER

  7. 15. Crimean-Congo hemorrhagic fever virus : interactions with host cell structures in viral replication

    Författare :Melinda Simon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Crimean-Congo hemorrhagic fever virus (CCHFV) is a human pathogen, and was first associated with its corresponding disease during an outbreak in the mid 1940s. At that time, outbreaks were mainly restricted to the former Soviet Union, Africa and Asia, but lately disease incidents have markedly risen and CCHFV is now also endemic in several countries in the Middle East and Europe. LÄS MER