Sökning: "vimentin"
Visar resultat 11 - 15 av 60 avhandlingar innehållade ordet vimentin.
11. The effect of astrocytes and reactive gliosis on neurogenesis and astrogenesis in mice
Sammanfattning : Astrocytes are the most common cell type in mammalian central nervous system (CNS). Glial fibrillary acidic protein (GFAP) and vimentin constitute intermediate filaments (known also as nanofilaments), a part of the cytoskeleton, in astrocytes. LÄS MER
12. Hyaluronan in malignant pleural mesothelioma with special reference to diagnosis, tumourbiology and prognosis
Sammanfattning : Malignant pleural mesothelioma (MPM), the primary malignant tumour of the pleural cavity, is an uncommon and treatment resistant tumour. The prognosis is poor. In many, but not all cases the concentration of hyaluronan (Hya) is increased in pleural effusion. The clinical relevance of Hya in MPM is not clear. LÄS MER
13. Assessing the impact of modulating protein degradation pathways in cancer
Sammanfattning : Proteins are macromolecules, essential constituents of the cells with various functions, such as providing structure to the cells, performing biochemical reactions, transporting molecules. The levels of cellular proteins are in a dynamic equilibrium and regulated by their synthesis and degradation rates. LÄS MER
14. Isolation and characterization of adult neural stem cells
Sammanfattning : Injury to the central nervous system (CNS) is one of man's most handicapping situations resulting in severe functional impairment and in some cases a vegetative state where life is supported artificially. The brain and spinal cord, constituting the CNS, have been viewed for decades as having limited capacity of regeneration with no neurogenesis in the adult. LÄS MER
15. Specific autoimmunity in rheumatoid arthritis : T cells, antibodies and genetic regulation
Sammanfattning : Complex interactions between genes and environmental factors may result in destruction of the body’s own cells and tissues by the immune system, i.e. autoimmunity. Rheumatoid arthritis (RA) is a chronic joint inflammation mediated by all arms of the immune system that can lead to tissue destruction and functional disabilities. LÄS MER