Sökning: "villous atrophy"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden villous atrophy.

  1. 1. Tissue transglutaminase autoantibodies in childhood celiac disease

    Författare :Daniel Agardh; Pediatrisk endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; Medicine human and vertebrates ; Medicin människa och djur ; Immunology; serology; transplantation; villous atrophy; T cells; serological marker; screening; intestinal mucosa; children; celiac disease; CD25; CD8; CD4; autoantibodies; B cells; gluten-free diet; autoimmunity;

    Sammanfattning : Celiac disease is a prevalent small bowel disease in children caused by permanent intolerance against gliadin, which is the alcohol-soluble fraction of the cereal protein gluten in wheat, rye and barley. Celiac disease is characterized by an inflammatory infiltrate of CD4+ T lymphocytes in the intestinal mucosa leading to damage of villous structure and loss of absorptive surface. LÄS MER

  3. 2. The Significance of IgG Antibodies against Tissue Transglutaminase in Coeliac Disease

    Författare :Ingrid Dahlbom; Birgitta Heyman; Tony Hansson; Knut Lundin; Uppsala universitet; []
    Nyckelord :Immunology; Coeliac disease; Tissue transglutaminase; Endomysium; IgG antibodies; Immunologi;

    Sammanfattning : Coeliac disease (CD) is a multifactorial disease of the small intestine. In genetically predisposed individuals the, ingestion of cereals leads to a remodulation of the mucosal architecture, and the production of autoantibodies against tissue transglutaminase (tTG). The treatment is a lifelong gluten-free diet. LÄS MER

  4. 3. Studies of Mucosal Immune Regulation in Celiac Disease and Type 1 Diabetes

    Författare :Anne Lahdenperä; Johnny Ludvigsson; Outi Vaarala; Rosaura Casas; Eva Sverremark-Ekström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Background: Celiac disease (CD) and type 1 diabetes (T1D) are two chronic autoimmune diseases with increasing incidence worldwide. A combination of genetic, environmental and immunological factors is considered to be involved in development of the diseases, even though the exact disease mechanisms still are unknown. LÄS MER

  5. 4. Bone in coeliac disease

    Författare :Trausti Valdimarsson; Pekka Collin; Linköpings universitet; []
    Nyckelord :Bone mineral density; coeliac disease; gluten-free diet; parathyroid hormone; insulin-like growth factor; MEDICINE; MEDICIN;

    Sammanfattning : Patients with untreated and treated coeliac disease were examined regarding bone mineral density (BMD) and biochemical factors of importance for bone metabolism. The occurrence of disturbances and their correction during treatment with a gluten-free diet were studied. LÄS MER

  7. 5. Immunopathogenesis of schistosomiasis mansoni : Immunity and pathology in a primary and a secondary infection following chemotherapy in the mouse and the baboo models

    Författare :Idle Omar Farah; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Baboon; BALB c mice; Chemotherapy; Cytokines; Fibrosis; Granuloma; Modulation; Pathology; Reinfection; Schistosoma mansoni; Th1; Th2; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Medicine; medicin;

    Sammanfattning : This thesis describes a series of experiments aimed at elucidating the mechanisms ofimmunity and pathology elicited by both a primary infection and a reinfection exposure toSchistosoma mansoni following chemotherapy. The effects of a single large cercarial doseand a cumulatively equivalent dose, administered as multiple small doses are compared. LÄS MER