Sökning: "vikingsson"

Hittade 3 avhandlingar innehållade ordet vikingsson.

  1. 1. Development of new methodology for therapeutic drug monitoring of thiopurine treatment

    Författare :Svante Vikingsson; Curt Peterson; Björn Carlsson; Martin Josefsson; Sven Almer; Johan Ahlner; Lynne Lennard; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thiopurines; mercaptopurine; thioguanine; azathioprine; crohn s disease; ulcertive colitis; HPLC; TGN;

    Sammanfattning : The three thiopurine drugs azathioprine (AZA), 6-mercaptopurine (6-MP) and 6-thioguanine (6-TG) are used to treat several diseases, including inflammatory bowel disease (IBD). They are pro-drugs and are believed to act through the formation of thioguanine nucleotides (TGNs). LÄS MER

  3. 2. Pharmacogenetic biomarkers for chemotherapy-induced adverse drug reactions

    Författare :Niclas Björn; Henrik Green; Svante Vikingsson; Joakim Lundeberg; Johan Staaf; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cancer is a serious disease expected to be the world-leading cause of death in the 21st century. The use of harsh chemotherapies is motivated and accepted but, unfortunately, is often accompanied by severe toxicity and adverse drug reactions (ADRs). LÄS MER

  4. 3. Toxicity and pharmacokinetic biomarkers for personalized non-small cell lung cancer treatment

    Författare :Anna Svedberg; Henrik Green; Svante Vikingsson; Joakim Lundeberg; Mikko Niemi; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Lung cancer is the leading cause of cancer-related deaths worldwide. Unfortunately, lung cancer is usually discovered at a late stage when the curative treatment options are limited. The treatment can include surgery, radiation, chemotherapy, targeted therapy and now also immunotherapy. LÄS MER