Sökning: "vesicle adsorption"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden vesicle adsorption.

  1. 1. On the Formation of Supported Phospholipid Bilayers

    Författare :Erik Reimhult; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; vesicle adsorption; formation kinetics; SPR; QCM-D; SPB; AFM; supported lipid bilayer; supported membrane; liposome;

    Sammanfattning : Lipid bilayers are a central component of both the structure and function of biological membranes, like the one surrounding cells of living organisms. Since the lipid bilayer provides a host matrix for membrane proteins, which perform many of the specialized tasks in cells like energy, signal and material transduction, researchers have tried to develop artificial model membranes to study a variety of membrane protein functions. LÄS MER

  2. 2. Interactions of the Cell-Penetrating Peptide Penetratin with Model Membranes and Live Cells

    Författare :Daniel Persson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antisense; antennapedia homeodomain; delivery vector; cell-penetrating peptide; protein transduction; uptake; membrane translocation; penetratin; confocal microscopy; vesicle;

    Sammanfattning : The delivery of large, hydrophilic molecules, such as proteins and oligonucleotides, to the cytoplasm and nucleus of cells is problematic due to their generally low plasma membrane permeability. With the identification of a number of cell-penetrating peptides, capable of mediating non-endocytotic, intracellular delivery of macromolecular cargos, this obstacle now seems surmountable. LÄS MER

  3. 3. Mesoporous supported lipid bilayers

    Författare :Maria Claesson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FRAP; Lipid bilayer; Mesoporous; AFM; Vesicle; Titania; Silica; QCM-D;

    Sammanfattning : AbstractLipid bilayers are commonly used as simplified model systems of living cell membranes. They have shown to be important components in the development of biosensing devices where the bilayer acts as a host for transmembrane proteins, such as ion channels, that are utilized as sensing elements. LÄS MER

  4. 4. Development of Ultra-fast Biosensors for Detection of Non-electroactive Neurotransmitters

    Författare :Yuanmo Wang; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; artificial cell; quantification; stability; deformation; dynamic light scattering; adsorption; amperometry; nanoparticle tracking analysis; enzyme monolayer; glucose oxidase; exocytosis; choline oxidase; acetylcholine; enzymatic activity; acetylcholine esterase; gold nanoparticles; Biosensor;

    Sammanfattning : During neuronal communication neurotransmitters are released through the process exocytosis that occurs on the time scale of sub-milliseconds to milliseconds. Neuronal activity by neurotransmitters that are non-electroactive cannot easily be monitored due to limitations in the temporal resolutions of the sensor probes for these analytes. LÄS MER

  5. 5. Creating Ultrafast Biosensors for Neuroscience

    Författare :Yuanmo Wang; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; quantification; glucose; choline oxidase; gold nanoparticles; enzyme monolayer; enzymatic activity; Biosensor; adsorption; brain slice; enzyme stability; acetylcholine esterase; artificial cell; exocytosis; glucose oxidase; deformation; glutamate; glutamate oxidase; acetylcholine; amperometry;

    Sammanfattning : Neuronal communication is the basis for all our brain function and relies on regulated exocytosis, a cell function that involves release of quantal amounts of neurotransmitters into the gap space between interconnected neurons to serve as chemical signals. To study exocytosis, which is a fast process that occurs on the timescale of sub-milliseconds to milliseconds, a toolbox of analytical methods has been developed where the electrochemical based techniques offer quantitative and sufficient high temporal recording speed. LÄS MER