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Visar resultat 1 - 5 av 19 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Pathophysiological and Histomorphological Effects of One-Lung Ventilation in the Porcine Lung

   Författare :Alf Kozian; Göran Hedenstierna; Thomas Hachenberg; Filip Freden; Sten Walther; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alveolar Recruitment Manoeuvre; One-Lung Ventilation; Lung Protective Ventilation; Tidal Volume; Computed Tomography; Tidal Recruitment; Animal Model; Open Thoracic Surgery; Ventilation Perfusion Distribution; Single Photon Emission Computed Tomography; Diffuse Alveolar Damage; Medical laboratory science; Medicinsk laboratorievetenskap; Anestesiologi; Anaesthesiology;

   Sammanfattning : Thoracic surgical procedures require partial or complete airway separation and the opportunity to exclude one lung from ventilation (one-lung ventilation, OLV). OLV is commonly associated with profound pathophysiological changes that may affect the postoperative outcome. LÄS MER

3. 2. Ventilation/Perfusion Matching and its Effect on Volatile Pharmacokinetics

   Författare :Moritz Andreas Kretzschmar; Anders Larsson; Jan Jakobsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anesthesia; Animal models in research; Mass spectrometry; Gas chromatography; MIGET; Ventilation-perfusion; Desflurane; Isoflurane; Bronchoconstriction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : The mismatching of alveolar ventilation and perfusion (VA/Q) is the major determinant of impaired gas exchange. The gold standard for analyzing VA/Q distribution is the multiple inert gas elimination technique (MIGET), conventionally based on gas chromatography (GC), and, although simple in principle, a technically demanding procedure limiting its use. LÄS MER

4. 3. Quantification of pulmonary scintigraphy

   Författare :Jiahua Xu; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Emphysema; Inhomogeneity; Perfusion; scintigraphy; SPECT; 99mTc-Technegas; Ventilation; V Q;

   Sammanfattning : Modern nuclear medicine techniques, such as SPECT (single photon emission computed tomography), enable quantification and localisation of lung function in small lung elements, but appropriate methods are not yet available. The aim of the present project was therefore to develop and evaluate methods for mapping lung function in planar scintigrams and in SPECT. LÄS MER

5. 4. Tomographic ventilation-perfusion lung scintigraphy in cardiopulmonary disease

   Författare :Jonas Jögi; Lund Klinisk fysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Technegas; Ventilation-Perfusion Single Photon Emission Computed Tomography; Chronic obstructive pulmonary disease; Heart failure; Pulmonary embolism;

   Sammanfattning : Respiration relies, among other things, on the balance between regional ventilation and perfusion in the lungs. There are many cardiopulmonary diseases, such as pulmonary embolism (PE), chronic obstructive pulmonary disease (COPD) and left heart failure (LHF), which can affect respiration negatively. LÄS MER

7. 5. The Effect of CO2-Pneumoperitoneum on Ventilation Perfusion Distribution of the Lung

   Författare :Christof Strang; Göran Hedenstierna; Suzanne Odeberg-Wernerman; Uppsala universitet; []
   Nyckelord :lung; atelectasis; computed tomography; multiple inert gas elimination technique; model; pig; Pa–ECO2 ratio; surgery; laparoscopy; lung; blood flow; single photon emission computed tomography; ventilation perfusion distribution; gas exchange; hypoxic pulmonary vasoconstriction; MEDICINE; MEDICIN;

   Sammanfattning : Laparoscopic operations are a common and popular way for abdominal procedures. They are usually performed by insufflation of carbon dioxide (CO2) into the abdominal cavity. However, insufflation of CO2 may interfere with cardiac and circulatory as well as respiratory functions. The CO2-pneumoperitoneum (PP) may cause hypercarbia and acidosis. LÄS MER