Sökning: "vein grafts"

Visar resultat 11 - 15 av 22 avhandlingar innehållade orden vein grafts.

  1. 11. Vascular Wall Responses to Bypass Grafting - Studies in Mice

    Författare :Klas Österberg; Göteborgs universitet; []
    Nyckelord :Intimal hyperplasia; graft stenosis; smooth muscle cells; mice; cellular recruitment;

    Sammanfattning : Abstract Vein grafts are frequently used in bypass surgery for treatment of coronary artery disease and lower limb ischemia. Unfortunately the long-term patency is impaired by vein graft stenoses due to intimal hyperplasia (IH). It is assumed that exaggerated intimal thickening is initiated by vessel wall injuries or local flow disturbances. LÄS MER

  3. 12. Studies on vascular remodeling in acute coronary artery disease

    Författare :Fei Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atherosclerosis; unstable angina; matrix metalloproteinase; apoptosis; angiogenesis; remodeling;

    Sammanfattning : Atherosclerosis is an arterial disease, characterized by endothelial dysfunction, vascular inflammation, and lipid accumulation in the vessel wall. Unstable coronary syndroms may be initiated by rupture of the atherosclerotic plaque, which may be caused by activation of matrix metalloproteinases (MMPs), apoptosis and angiogenesis. LÄS MER

  4. 13. The anterior chamber of the eye as an islet transplantation site in type-2 diabetes

    Författare :Sai Bo Bo Tun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetes mellitus is a chronic disease, one of the leading causes of death and a consistent financial burden globally. It occurs when insulin is insufficient for glucose homeostasis. Pancreatic islet transplantation drew attention as an attractive therapeutic option for treating Type-1 diabetes. LÄS MER

  5. 14. Clinically-driven angiography after coronary artery bypass surgery : Results from the SWEDEHEART registry

    Författare :Mikael Janiec; Rickard Lindblom; Stefan Thelin; Alexander Wahba; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CABG; Coronary artery bypass surgery; angiography; graft failure; Thorax Surgery; Thoraxkirurgi;

    Sammanfattning : The success of coronary artery bypass grafting (CABG) arguably depends on the patency rate of the conduits. The saphenous vein grafts (SVGs) most often used are subject to graft disease and their reduced long-term patency compared to left internal mammary artery (IMA) grafts is well established. LÄS MER

  7. 15. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets

    Författare :Joey Lau; Per-Ola Carlsson; Leif Jansson; Carina Carlsson; Caroline Kampf; Annika Tibell; Uppsala universitet; []
    Nyckelord :Cell biology; Type 1 diabetes; pancreatic islets; human islets; islet transplantation; vascular engraftment; revascularization; implantation-site; microenvironment; vascular density; insulin release; pro insulin biosynthesis; glucose oxidation; Cellbiologi;

    Sammanfattning : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. LÄS MER