Sökning: "vascular smooth muscle cell"

Visar resultat 11 - 15 av 132 avhandlingar innehållade orden vascular smooth muscle cell.

  1. 11. On cellular sources for intimal hyperplasia after vascular interventions

    Författare :Stefan Mellander; Göteborgs universitet; []
    Nyckelord :intimal hyperplasia; vascular intervention; smooth muscle cell; blood-born mononuclear cell; prosthetic graft; balloon injury; pig; rabbit;

    Sammanfattning : Vascular interventions for the treatment of symptomatic atherosclerosis fail in up to 40 % of the cases during the first year. One important reason is the development of a narrowing process known as intimal hyperplasia (IH). The cells forming IH resemble smooth muscle cells (SMCs) from the media of the arterial wall. LÄS MER

  3. 12. Injury-Induced Signalling in Arterial Smooth Muscle Cells

    Författare :Sara Moses; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GAG; Clinical biology; Klinisk biologi; proteoglycan; osteopontin; ERK; MAPK; signalling; smooth muscle cell; injury;

    Sammanfattning : The vascular wall is an active, elastic and integrated organ made up of cellular and extracellular matrix (ECM) components. It is not a static organ; the components dynamically change and reorganize in response to physiological and pathological stimuli. Vascular injury induces a complex healing process, analogous to generalised wound healing. LÄS MER

  4. 13. Medin Amyloid in Human Arteries and its Association with Arterial Diseases

    Författare :Siwei Peng; Per Wstermark; Gunnar Husby; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Amyloid; Medin; Lactadherin; Aneurysm; Aortic dissection; Temporal artery; Arteritis; Giant cell; Pre-aggregation.; Patologi; Pathology; Patologi;

    Sammanfattning : Amyloid is a form of abnormal protein aggregation within the living body. Massive deposits can lead to organ failure. There is also increasing evidence that smaller pre-amyloid aggregates exert direct toxic effects to cells. LÄS MER

  5. 14. Synchronized delivery of inspired nitric oxide : Effects on oxygenation and pulmonary tension during artificial ventilation

    Författare :Erkki Heinonen; Tim Higenbottam; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; nitric oxide; pulsed administration; pulmonary hypertension; oxygenation; equine; Cellbiologi; Cell biology; Cellbiologi; Physiology; fysiologi;

    Sammanfattning : Nitric oxide (NO) is a mediator of vascular smooth muscle tension that metabolises rapidly in blood. NO delivered by inhalation can therefore be used as a selective pulmonary vasodilator to relieve pulmonary hypertension or to improve oxygenation with no systemic effects. LÄS MER

  7. 15. Signal transduction and calcium sensitivity of smooth muscle contraction

    Författare :Johan Bonnevier; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; hypertrophy; CPI-17; MYPT1; myosin phosphatase; Rho kinase; PKC; smooth muscle; cGK;

    Sammanfattning : Smooth muscles are components of several physiologically important organs and often involved in disease. Smooth muscle contraction is regulated by variations in intracellular [Ca2+]; increased levels activate the myosin light chain kinase (MLCK) which phosphorylates myosin and initiates contraction. LÄS MER