Sökning: "vascular remodelling"

Visar resultat 6 - 10 av 40 avhandlingar innehållade orden vascular remodelling.

  1. 6. Fluid biomarkers of extracellular matrix remodelling across neurological diseases

    Författare :Karolina Minta; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; extracellular matrix; idiopathic normal pressure hydrocephalus; immunoassay; mass spectrometry; radiation-induced brain injury; traumatic brain injury; vascular dementia;

    Sammanfattning : Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. LÄS MER

  3. 7. Functions of Pericytes in Ischemic Stroke

    Författare :Michaela Roth; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; Pericytes; RGS5; Blood-brain barrier; vascular remodelling; scar formation;

    Sammanfattning : Ischemic stroke remains one of the leading causes of death and disability worldwide, and its burden is predicted to further increase due to the aging population. The only available treatments, thrombolysis or thrombectomy, can only be applied within a limited time window after stroke onset, and thus are applicable only to a small proportion of stroke patients. LÄS MER

  4. 8. Atherosclerosis in 64-year-old women with diabetes mellitus and impaired glucose tolerance

    Författare :Gerhard Brohall; Göteborgs universitet; []
    Nyckelord :Systematic review; Atherosclerosis; Type-2 diabetes; IMT; Vascular remodelling; IGT;

    Sammanfattning : Atherosclerosis in 64-year-old women with diabetes mellitus and impaired glucose tolerance The incidence of obesity and type-2 diabetes (t2D) is rising around the world. T2D is accompanied by an increased risk of macrovascular, atherosclerotic diseases. LÄS MER

  5. 9. Matrix degrading proteases in vascular disease

    Författare :Sofia Jormsjö-Pettersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atherosclerosis; abdominal aortic aneurysm; MMP; cathepsin; polymorphism; in vitro; proteases; extracellular matrix.;

    Sammanfattning : Diverse processes of vascular disease including lesion growth, plaque rupture and abdominal aortic aneurysm formation are influenced by protease expression. Arteries undergo compensatory remodelling when the mechanical forces that are imposed on them are altered. LÄS MER

  7. 10. Retinoid metabolism and signalling in vascular smooth muscle cells

    Författare :Pauline Ocaya; Allan Sirsjö; Andreas C. Gidlöf; William S. Blaner; Örebro universitet; []
    Nyckelord :all-trans Retinol; all-trans Retinoic acid; retinoid metabolism; proliferation; Vascular smooth muscle cells; CYP26; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Sammanfattning : Smooth muscle cells (SMCs) play a major role in cardiovascular diseases. In advanced atherosclerosis, blood flow is impaired due to reduced luminal diameter. Percutaneous vascular interventions, including balloon angioplasty and stent-application are commonly used for the re-establishment of luminal size and improvement of tissue perfusion. LÄS MER