Sökning: "vascular permeability"

Visar resultat 16 - 20 av 90 avhandlingar innehållade orden vascular permeability.

  1. 16. A close-up on neutrophils : Visualizing the mechanisms of their in vivo recruitment and function

    Författare :Sara Massena; Mia Phillipson; Randall S. Jonhson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; chemokine; chemotactic gradient; citrullination; hypoxia; inflammation; intraluminal crawling; intravital imaging; PAD enzymes; permeability; proangiogenic; proinflammatory;

    Sammanfattning : A successful immune response depends on prompt and sufficient recruitment of leukocytes from the circulation to infected or injured sites. Mobilization of leukocytes to hypoxic tissues is vital for angiogenesis, i.e. the formation of new blood vessels from preexisting vasculature, and thus crucial for tissue growth and regeneration. LÄS MER

  2. 17. Capillary and interstitial transport of fluid and solutes across the peritoneal membrane

    Författare :Ola Carlsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular resistance.; capillary pressure; aquaporins; Capillary permeability; vesicular transport; Urology; nephrology; Urologi; nefrologi;

    Sammanfattning : According to the three-pore model of peritoneal transport the major exchange pathway between the blood and the peritoneal cavity is represented by “small pores”, permeable to small solutes and water. Osmotically induced fluid flow, as during peritoneal dialysis (PD), is postulated to occur to a great extent through a water-only pathway, whereas proteins are predicted to reach the peritoneal cavity by unidirectional convection across “large pores”. LÄS MER

  3. 18. Vascular targeting for enhanced cancer immunotherapy

    Författare :Maria Georganaki; Anna Dimberg; Sara Mangsbo; Lena Claesson-Welsh; Wolf Hervé Fridman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; tumor vasculature; endothelial activation; IDO1; ELTD1; tertiary lymphoid organ; Biologi; Biology;

    Sammanfattning : Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The scope of this thesis is to understand the role of the vasculature in anti-tumor immunity and thereby to improve cancer immunotherapy. LÄS MER

  4. 19. Shock wave effects on the vascular endothelium

    Författare :Anders Sondén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Shock waves; cavitation; explosions; high-energy missile trauma; ESWL; laser; endothelial cells; cell membrane damage; cytoskeleton; adhesion molecules; reactive oxygen species;

    Sammanfattning : A shock wave is a pressure wave with high amplitude and a velocity above sound. Man is exposed to shock waves (SWs) in connection with trauma, e.g. explosions and high-energy missiles and medical treatments such as extracorporeal lithotripsy (ESWL). LÄS MER

  5. 20. VEGF-mediated vascular functions in health and disease

    Författare :Ziquan Cao; Eric Wahlberg; Yihai Cao; Toste Länne; Kayoko Hosaka; Jack L. Arbiser; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Angiogenesis is essential for physiological processes including embryonic development, tissue regeneration, and reproduction. Under various pathological conditions the same angiogenic process contribute to the onset, development, and progression of many human diseases including cancer, diabetic complications, ocular disease, chronic inflammation and cardiovascular disease. LÄS MER