Sökning: "vascular endothelial growth factor VEGF"

Visar resultat 21 - 25 av 128 avhandlingar innehållade orden vascular endothelial growth factor VEGF.

1. 21. Collagenous Colitis : A Study of Inflammatory Mediators and Growth Factors Based on Segmental Colorectal Perfusion and Immunohistochemistry

   Författare :Yesuf Ahmed Taha; Magnus Thörn; Yngve Raab; Lars Lööf; Mikael Lördal; Curt Tysk; Uppsala universitet; []
   Nyckelord :General; Collagenous; Collagenous colitis; inflammatory mediators; Steroid treatment; Eosinophil Cationic Protein; Basic Fibroblast Growth Factor bFGF ; Vascular Endothelial Growth Factor VEGF ; albumin; ALLMÄNT;

   Sammanfattning : Collagenous colitis (CC) is an inflammatory bowel disease of unknown etiology. It is characterized by watery diarrhoea without blood, normal endoscopic findings but microscopically colonic mucosal inflammation and increased thickness of the subepithelial collagen band, the latter being a pathognomonic sign. LÄS MER

3. 22. Molecular mechanisms of VEGF-mediated angiogenesis and vascular permeability

   Författare :Anna Eriksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Angiogenesis; VEGF; vascular permeability;

   Sammanfattning : Angiogenesis, sprouting of new capillaries from pre-existing blood vessels, is a tightly regulated multi-step process. One of the key mediators in this process is the Vascular Endothelial Growth Factor (VEGF). Many tumors express high levels of VEGF and pathological angiogenesis is considered a hallmark of malignant tumor growth. LÄS MER

4. 23. Role of extracellular retention of platelet-derived growth factor-B. Functions in development and disease

   Författare :Per Lindblom; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; pericyte; cancer; fibrosis; ECM; HSPG; cell retention; endothelial;

   Sammanfattning : During development, the cell secretes growth and differentiation factors (GDFs) to the surrounding microenvironment. These factors are often key regulators of organogenesis and embryogenesis. Several GDFs carry sequences that mediate specific interaction with molecules of the extracellular matrix (ECM) that surrounds the cell. LÄS MER

5. 24. Effects of Ischaemia on the Neuroretina and Retinal Blood Vessels

   Författare :Bodil Gesslein; Lund Oftalmologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein kinase C; tumor necrosis factor; mitogen-activated protein kinases; pig; blood vessels; mfERG; Retinal ischaemia; vascular endothelial growth factor; hypoxia-inducible factor;

   Sammanfattning : Identification of the intracellular signal transduction pathways activated in retinal ischaemia may be important in revealing novel pharmacological targets. The retinal blood vessels are key organs in circulatory failure, and in this work the retinal vasculature was therefore examined separately from the neuroretina. LÄS MER

7. 25. New Roles of Filamins in Cell Signaling, Transcription and Organ Development

   Författare :Xianghua Zhou; Göteborgs universitet; []
   Nyckelord :filamins; cell movement; hypoxia-inducible factor 1; proto-oncogene proteins c-met; mice; knockout; F-actin-binding proteins; integrins; GTB phosphohydrolases; genetic diseases; inborn; vascular endothelial cell growth factor A; Smad2 protein; hepatocyte growth factor; cartilage; osteogenesis; neovascularization; neoplasm metastasis;

   Sammanfattning : Filamins are large actin-binding proteins that stabilize delicate three-dimensional actin networks and link them to cellular membranes. They integrate cell architectural and signaling functions and are essential for cell locomotion and development. LÄS MER