Sökning: "vaginal carcinoma"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden vaginal carcinoma.

1. 1. Characterization of HPV-induced vaginal and vulvar carcinoma

   Författare :Gabriella Lillsunde-Larsson; Mats G. Karlsson; Gisela Helenius; Sonia Andersson; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vaginal carcinoma; vulvar carcinoma; HPV; integration; methylation; genotyping; Medicine; Medicin;

   Sammanfattning : .... LÄS MER

3. 2. Leucine-rich repeats and immunoglobulin-like domain (LRIG) proteins : possible prognostic markers in vulvar squamous cell carcinoma, endometrial carcinoma, and oropharymgeal squamous cell carcinoma

   Författare :Husam Oda; David Lindquist; Eva Lundin; Ulrika Ottander; Kristina Stefansson; Kate Cuschieri; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vulvar squamous cell carcinoma; endometrial carcinoma; oropharyngeal squamous cell carcinoma; LRIG1-3; HPV; LMO7; HPV-driven; non-HPV-driven; prognosis; overall survival; disease-free survival; p53; Ki-67; CD8 TILs; CD44.; Pathology; patologi;

   Sammanfattning : The human leucine-rich repeats and immunoglobulin-like domain (LRIG) gene family comprises three genes, LRIG1, LRIG2 and LRIG3, which encode the LRIG1, LRIG2 and LRIG3 proteins, respectively. Previous stidies have revealed the different prognostic roles of these proteins in different cancers, and it has been shown that LRIG1 functions as a tumour suppressor in certain cancers via its negative regulation of several receptor tyrosine kinases. LÄS MER

4. 3. Vaginal carcinoma : studies on etiology and prognostic factors

   Författare :Kristina Hellman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Primary vaginal carcinoma; genesis; etiology; prognosis; lammin-5gamma2 chain; CGH; genomic instability; protein expression; hierarchical cluster analysis;

   Sammanfattning : Primary carcinoma of the vagina (PCV) is a rare disease, with poor survival, mostly affecting elderly women. Due to its rarity the established knowledge originates from studies based on small materials, therefore little is known regarding the genesis, natural history and factors predicting the prognosis. LÄS MER

5. 4. HPV and potential prognostic markers in primary vaginal carcinoma

   Författare :Cecilia Ranhem; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The overall aim of this PhD thesis is to evaluate HPV status and immunohistochemical expression of different biomarkers, including tumor suppressor p16, proliferation marker Ki67, molecular markers in the LRIG family, WRAP53ß, and dyskerin as well as immune markers CD4+ and CD8+ TILs, and their correlation to clinical manifestations and survival as part of a search for potential prognostic factors in women diagnosed with primary vaginal cancer. Paper I evaluates the presence of HPV in vaginal cancer tumor samples, as well as immunohistochemical expression of p16 and Ki-67. LÄS MER

7. 5. Endometrial carcinoma : prognostic factors and protein expression profiling

   Författare :Caroline Lundgren; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Endometrial carcinoma; prognosis; DNA ploidy; MIB-1; p53; laminin-5 72 chain; 2DE;

   Sammanfattning : Endometrial carcinoma is the most common gynaecological cancer in the western world. It is usually diagnosed at an early stage since it presents with irregular vaginal bleeding when the tumour is still limited to the uterus and the prognosis is generally favourable. LÄS MER