Sökning: "vacuolisation"

Hittade 3 avhandlingar innehållade ordet vacuolisation.

  1. 1. Of mice and men : SOD1 associated human amyotrophic lateral sclerosis and transgenic mouse models

    Författare :Karin Sixtensdotter Graffmo; Thomas Brännström; Stefan Marklund; Elisabeth Englund; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aggregates; ALS; amyotrophic lateral sclerosis; inclusions; misfolded; vacuolisation; SOD1; transgenic; Pathology; Patologi;

    Sammanfattning : Amyotrophic lateral sclerosis, ALS, is a progressive fatal neurodegenerative disorder affecting motor neurones in motor cortex, brain stem and spinal cord. This inevitably leads to paralysis, respiratory failure and death. LÄS MER

  3. 2. Elucidating the role of 17β hydroxysteroid dehydrogenase type 14 in normal physiology and in breast cancer

    Författare :Tove Sivik; Agneta Jansson; Olle Stål; Lars-Arne Haldosén; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Oestrogens play key roles in the development of the majority of breast tumours, a fact that has been exploited successfully in treating breast cancer with tamoxifen, which is a selective oestrogen receptor modulator. In post-menopausal women, oestrogens are synthesised in peripheral hormone-target tissues from adrenally derived precursors. LÄS MER

  4. 3. Respiratory tract infections, reflex apnea and sudden infant death : experimental and epidemiological studies with special reference to respiratory syncytial virus, Bordetella pertussis and sleep position

    Författare :Carl Lindgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Bordetella pertussis; Infection; Interleukins; Laryngeal chemoreflex; Respiratory syncytial virus; Reflex apnea; Sleep; Sleeping position; Sudden infant death;

    Sammanfattning : The seasonal distribution of Sudden infant death syndrome (SIDS) followed the prevalence of respiratory tract infections (RTI) when prone sleeping position was recommended, but this covariation has recently been attenuated. Airway infections in the young infant are known to produce respiratory disturbances. LÄS MER