Sökning: "vaccine"

Visar resultat 11 - 15 av 492 avhandlingar innehållade ordet vaccine.

  1. 11. Characterisation of Neisseria meningitidis from a virulence and immunogenic perspective that includes variations in novel vaccine antigens

    Författare :Susanne Jacobsson; Hans Fredlund; Per Olcén; Paula Mölling; Elisabeth Wedege; Örebro universitet; []
    Nyckelord :Neisseria meningitidis; meningococcal disease; risk factors; vaccine; genome-derived neisserial antigens GNA ; polymerase chain reaction PCR ; sequencing; MEDICINE; MEDICIN; Medicin; Medicine; Biomedicin; Biomedicine;

    Sammanfattning : Neisseria meningitidis, also referred to as meningococcus, is a Gram-negative diplococcal bacterium best known as an important cause of meningitis and septicaemia worldwide. Meningococcal disease is a rare but life-threatening illness that may progress to death despite optimal medical care including appropriate antibiotic therapy. LÄS MER

  2. 12. PROTEIN VACCINE AGAINST NEONATAL GROUP B STREPTOCOCCAL INFECTION Immunization experiments in animals and a serological study in humans

    Författare :Charlotte U Larsson; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bakteriologi; mycology; bacteriology; Microbiology; virologi; mykologi; neonatal infection; human antibody; intranasal; vaccine; cholera toxin B subunit; Rib; α; Group B streptococcus; surface protein; Mikrobiologi; virology;

    Sammanfattning : Infection with group B streptococcus (GBS), an encapsulated bacterium, is an important cause of neonatal morbidity and mortality. Capsular polysaccharides and cell surface proteins of GBS are candidate antigens for development of a human GBS vaccine. Proteins have many advantages as vaccine antigens. LÄS MER

  3. 13. Development of a New Oral Vaccine against Diphtheria and the Study of its Immunogenicity in Mouse and Man

    Författare :Niclas Rydell; Ingvar Sjöholm; Sveinbjörn Gizurarson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; oral vaccination; mucosal vaccination; diphtheria; biodegradable; microparticles; starch; CRM197; adjuvant; vaccine; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : Most pathogens enter the body via mucosal surfaces. In contrast to parenterally administered vaccination, mucosal vaccination has the advantage of eliciting both a systemic and a local mucosal immune response. An oral biodegradable adjuvant with these features would have great potential. LÄS MER

  4. 14. Development of novel vaccine strains of Vibrio cholerae and studies on the role of serotype in epidemic spread of cholera

    Författare :Stefan Karlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholera; Vibrio cholerae; Serotype; Ogawa; Inaba; Hikojima; Vaccine; Immunogenicity; serotype switching; wbeT;

    Sammanfattning : Cholera, caused by bacterium Vibrio cholerae O1, is a severe diarrheal disease with an estimated 3-5 million cases and more than 140 000 deaths every year particularly affecting children under 5 years of age. It can be found all over the world and often causes cholera in places where access to clean water or proper sanitary facilities are limited or compromised. LÄS MER

  5. 15. Impact of the inflammatory response on specific immunity in neurosurgical patients

    Författare :Anna Ljunghill Hedberg; Jan Sjölin; Karlis Pauksen; Lars Hagberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T-cell-dependent vaccine; T-cell-independent vaccine; CNS injury-induced immune deficiency syndrome; pneumococcal conjugate vaccine; pneumococcal polysaccharide vaccine; posttraumatic meningitis.; Medicinsk vetenskap; Medical Science; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Vaccination with a T-cell-dependent pneumococcal conjugate vaccine (PCV) followed by a T-cell-independent pneumococcal polysaccharide vaccine (PPSV) is recommended after basilar skull fracture to reduce the risk of meningitis. The optimal time frame for vaccination has not yet been established and varies widely in practice. LÄS MER