Sökning: "västafrika"

Visar resultat 16 - 20 av 22 avhandlingar innehållade ordet västafrika.

  1. 16. HIV-1 evolution, disease progression and molecular epidemiology of HIV-1 single and HIV-1 and HIV-2 dual-infected individuals in Guinea-Bissau

    Författare :Joakim Esbjörnsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HIV-2; Guinea-Bissau; subtype; disease progression; evolution; coreceptor tropism; CXCR4; gp120; V1-V3; CD4%; CD8%; soluble immune markers;

    Sammanfattning : The two genetically related human lentiviruses known today, HIV-1 (which is pandemic) and HIV-2 (which mainly is confined to West Africa), are the causative agents of AIDS. Progressive immune dysfunction and AIDS develop in most cases of untreated HIV-1 infection, but only in approximately 25-30% of HIV-2 infected individuals. LÄS MER

  3. 17. Dynamics of HIV coreceptors and their utilization by plasma and cerebrospinal fluid HIV-1 isolates

    Författare :Ulf Karlsson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : HIV-1 infection of CD4+ immune cells requires the assistance of cellular coreceptors. The regulation of these receptors is highly dynamic. In addition to the major coreceptors, CCR5 and CXCR4, several alternative coreceptors mediate entry for selected HIV isolates in vitro, although their role in vivo is yet to be established. LÄS MER

  4. 18. HIV-1, HIV-2 and other Sexually Transmitted Infections in Guinea-Bissau, West Africa

    Författare :Fredrik Månsson; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1 HIV-2 Sexually Transmitted Infections Conflict Guinea-Bissau West Africa;

    Sammanfattning : HIV-1 is dominating the global HIV pandemic, while HIV-2 is mainly confined to West Africa. The highest HIV-2 prevalence figures have been reported from Guinea-Bissau. LÄS MER

  5. 19. Avian MHC: variation and selection in the wild

    Författare :Helena Westerdahl; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polymorphism; balancing selection; cDNA; avian malaria; great reed warbler; Djurekologi; bird; Animal ecology; immune defence; MHC class II; Major Histocompatibility Complex; MHC class I;

    Sammanfattning : In vertebrates the Major Histocompatibility Complex (MHC) plays a central role in the specific immune defence against various pathogens. Compared with other coding genes the MHC genes exhibit an extremely high level of polymorphism that is maintained by balancing selection. LÄS MER

  7. 20. HIV-2 infection in Guinea-Bissau, West Africa, with special reference to clinical, immunological and epidemiological aspects

    Författare :Hans Norrgren; Sektion III; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infections; Africa; Guinea-Bissau; AIDS; HIV-1; HIV-2; Infektioner;

    Sammanfattning : We have followed a cohort of police officers in Guinea-Bissau between 1990 and 1997 for the study of clinical, immunological and epidemiological aspects of HIV-2 infection. Initially the prevalence of HIV-2 was high (11.6 %) and HIV-1 infection was rare (0. LÄS MER