Sökning: "utvecklingsbiologi"
Visar resultat 6 - 10 av 255 avhandlingar innehållade ordet utvecklingsbiologi.
6. Mating type switching and transcriptional silencing in Kluyveromyces lactis
Sammanfattning : To explore the similarities and differences of regulatory circuits among budding yeasts, we characterized the role of unscheduled meiotic gene expression 6 (UME6) and a novel mating type switching pathway in Kluyveromyces lactis. We found that Ume6 was required for transcriptional silencing of the cryptic mating-type loci HMLα and HMRa. LÄS MER
7. Grainy head target genes in epithelial morphogenesis and wound healing
Sammanfattning : grainy head (grh) genes encode a family of transcription factors conserved from fly to human. Drosophila grh is the founding member of this gene family and has multiple functions, including tracheal tube size control, epidermal barrier formation and reconstruction after wounding. LÄS MER
8. Transcriptional Silencing in the Imprinted Igf2-H19 Loci: The Mystique of Epigenetics
Sammanfattning : Genomic imprinting marks a subset of autosomal loci expressed in parent of origin-dependent monoallelic expression in a non-Mendelian fashion. To restore totipotency and to reset the imprint according to the sex of the individual, the mark must be erased during germline development. LÄS MER
9. Epigenetic Regulation of Higher Order Chromatin Conformations and Gene Transcription
Sammanfattning : Epigenetic states constitute heritable features of the chromatin to regulate when, where and how genes are expressed in the developing conceptus. A special case of epigenetic regulation, genomic imprinting, is defined as parent of origin-dependent monoallelic expression. LÄS MER
10. Epigenetic Regulation and Reprogramming of the H19 Imprinting Control Region
Sammanfattning : The development of a new individual from the fertilized oocyte can ultimately be seen as the consequence of the establishment and maintenance of specific patterns of gene expression. Although regulation of gene activity occurs at different levels, cellular specialization and differentiation are the results of developmental cues that essentially take place at the transcriptional level. LÄS MER