Sökning: "urothelium"

Visar resultat 11 - 15 av 15 avhandlingar innehållade ordet urothelium.

  1. 11. Regulation of inducible nitric oxide synthase - Consequences in experimental models of bladder disease

    Författare :Rebecka Johansson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacy; toxicology; Farmakologi; smooth muscle-myosin heavy chain; Pharmacological sciences; pharmacognosy; farmakognosi; farmaci; actin; BDNF; Rho; aminoguanidine; TNF-alpha; IL-1beta; hypertrophy; differentiation; smooth muscle; bladder; nitric oxide; inducible nitric oxide synthase; toxikologi;

    Sammanfattning : Inducible nitric oxide synthase (iNOS) expression is associated with various pathophysiological conditions in the lower urinary tract. The aims of this thesis have been to investigate the regulation of iNOS in bladder smooth muscle cells and the consequences on neuromuscular regulation, cell growth and differentiation. LÄS MER

  3. 12. Urinary bladder carcinoma, preclinical and clinical studies on EGFR based targeting

    Författare :Peter Bue; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; urinary bladder carcinoma; epidermal growth factor-dextran; radionuclide therapy; Kirurgi; Surgery; Kirurgi; kirurgi; särskilt urologi; Urology;

    Sammanfattning : Radical cystectomy with bilateral pelvic lymphadenectomy is the standard treatment for muscle-invasive transitional cell carcinoma of the urinary bladder. Despite presumably localised malignancies and efficacious management about 50% of patients will die within 5 years, the majority due to metastatic disease. LÄS MER

  4. 13. Role of estrogen receptor beta in mouse prostate and bladder with references to human diseases

    Författare :Otabek Imamov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : After the discovery of estrogen receptor beta (ERbeta) in 1995, it became clear that in many non-classical estrogen-responsive organs, were in fact direct targets for estrogen. One of these organs is prostate gland, where ERbeta is abundant in epithelium. LÄS MER

  5. 14. On the autonomic control of the lower urinary tract. Functional and morphological aspects in the normal and the inflamed urinary bladder

    Författare :Daniel Giglio; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscarinic receptor; purinoceptor; adrenoceptor; nitric oxide; in vitro; in vivo; cystometry; Western blot; immunohistochemistry; cystitis; cyclophosphamide; urinary bladder; rat;

    Sammanfattning : The regulation of urinary bladder function involves interplay of signalling systems. Disturbances in any of the interactive systems may result in lower tract dysfunction, which is often apparent to the patient by urge to void or by incontinence, irrespectively of the cause to the lower tract syndrome. LÄS MER

  7. 15. Regenerative medicine and register studies related to bladder exstrophy

    Författare :Gisela Reinfeldt Engberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Bladder exstrophy is a rare congenital malformation affecting both boys and girls. The malformation involves the bladder, the urethra, genitalia, and pelvis. The child presents with a defect of the lower abdominal wall exposing an open bladder. LÄS MER