Sökning: "urologi 2011"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden urologi 2011.

  1. 1. Early diagnosis and treatment of prostate cancer : observational studies in the National Prostate Cancer Register of Sweden and the Västerbotten Intervention Project

    Författare :Benny Holmström; Pär Stattin; Håkan Jonsson; Mattias Johansson; Gunnar Aus; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; prostate-specific antigen; single nucleotide polymorphism; Urology and andrology; Urologi och andrologi; Urology; kirurgi; särskilt urologi;

    Sammanfattning : Prostate-specific antigen (PSA) testing has caused a steep increase in the incidence of prostate cancer, especially the incidence of localised low risk disease. In order to decrease the overdiagnosis accompanied by PSA testing, analysis of inherited genetic variants have been suggested as potential tools for clinical assessment of disease risk. LÄS MER

  2. 2. Quality of Life and Functional Outcomes in Men with Localized Prostate Cancer

    Författare :Eva Johansson; Anna Bill-axelson; Anders Widmark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; radical prostatectomy; watchful waiting; quality of life; erectil dysfunction; androgen deprivation therapy; robot-assisted radical prostatectomy; inguinal hernia; information; randomized; Urology and andrology; Urologi och andrologi; Urologi; Urology;

    Sammanfattning : Quality-of-life and functional outcomes are important in the choice of treatment for men with localized prostate cancer. These issues were investigated in the present thesis. All living 400 men randomized to radical prostatectomy or watchful waiting from 1989 to 1999 in the Scandinavian Prostate Cancer Group Number 4 (SPCG-4) were included. LÄS MER

  3. 3. Dynamics of the glomerular filtration barrier - Physiological and pathophysiological aspects

    Författare :Josefin Axelsson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Glomerular permeability; Microalbuminuria; Albumin; Ficoll; Sieving Coefficient; Rats;

    Sammanfattning : The dynamic properties of the glomerular filtration barrier (GFB) are of fundamental importance for the understanding of the physiology and pathophysiology of microalbuminuria and proteinuric diseases. In the studies of this doctoral thesis the properties of the rat glomerular filtration barrier were investigated under resting conditions and following a number of challenges using highly sensitive gel filtration chromatography (HPSEC) detection of FITC-Ficoll in serum and urine. LÄS MER

  4. 4. Translational perspectives on MSMB and CRISP3 expression and regulation in prostate cancer

    Författare :Anna K Dahlman; Malmö Urologisk cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Prostate cancer is currently the most common form of cancer in Sweden. Currently, the only biomarker used in the clinic is serum PSA, and there is a great need for new biomarkers that may increase the diagnostic and prognostic information so that better predictions can be made, and treatment may be tailored. LÄS MER

  5. 5. Prognostic markers in prostate cancer : studies of a watchful waiting cohort with long follow up

    Författare :Andreas Josefsson; Anders Bergh; Pernilla Wikström; Pär Stattin; Anders Bjartell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Immunohistochemistry; Prognostic markers; biomarkers; Survival analysis; human; pathology; watchful waiting; tissue micro array; Endoglin; von willebrandt factor; ki67; ki-67; hyaluronan; patologi; Pathology;

    Sammanfattning : Background: Prostate Cancer (PC) is a common and highly variable disease. Using current diagnostic methods, the prostate specific antigen (PSA) blood test and histological grading of prostate tissue needle biopsies, it is often difficult to evaluate whether the patient has a PC that requires active treatment or not. LÄS MER