Sökning: "up-regulation"

Visar resultat 16 - 20 av 316 avhandlingar innehållade ordet up-regulation.

  1. 16. Macroalgal community dynamics on coral reefs : Implications for management

    Författare :Erik Mörk; Nils Kautsky; Magnus Nyström; Tim R. McClanahan; Stein Fredriksen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Macroalgae; Coral Reefs; Herbivory; Nutrients; Ecosystem change; Fish; Sea Urchins; East Africa; marin ekotoxikologi; Marine Ecotoxicology;

    Sammanfattning : Although rather inconspicuous on healthy coral reefs, macroalgae form the basis of coral food webs. Today, macroalgae are generally increasing and many reefs undergo transitions from coral to macroalgal dominance resulting from e.g. enhanced nutrient loading or increased fishing. LÄS MER

  3. 17. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma

    Författare :Yaping Zhang; Klinisk och experimentell allergiforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; farmakognosi; MAPK; TNF-alpha; 5-HT; Respiratory system; Andningsorganen; Pharmacological sciences; pharmacognosy; pharmacy; interleukin-1beta; hyperresponsiveness; endothelin-1; airway; bradykinin; toxikologi; farmaci;

    Sammanfattning : Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. LÄS MER

  4. 18. The role of the deubiquitinating enzyme CYLD and its substrate BCL-3 in solid tumors

    Författare :Kristofer Ahlqvist; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The tumor suppressor CYLD and the proto-oncogene BCL-3 are known to be deregulated in various cancer types. The molecular background of how these genes participate in carcinogenesis is not fully understood. LÄS MER

  5. 19. Pharmacological interventions against myocardial ischemia and reperfusion injury

    Författare :Lars O Karlsson; Göteborgs universitet; []
    Nyckelord :Myocardial reperfusion injury; opioids; cyclosporine A;

    Sammanfattning : Background: Ischaemic heart disease is the leading cause of death in the industrialised world. Although the concept of early restoration of coronary blood-flow constitutes an important factor to reduce the injury caused by myocardial ischaemia, reperfusion in itself can aggravate the damage to myocardial tissue, a phenomenon denoted myocardial reperfusion injury. LÄS MER

  7. 20. The return of the nucleus : epigenetic regulation of autophagy

    Författare :Jens Füllgrabe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autophagy is an evolutionary conserved catabolic process activated in response to a variety of cellular stresses, for example nutrient deprivation or chemotherapy. During autophagy, cells engulf parts of their cytplasm in a double-membrane vesicle, where misfolded proteins or damaged organelles are degraded. LÄS MER