Sökning: "tyrosyl radical"

Visar resultat 11 - 15 av 17 avhandlingar innehållade orden tyrosyl radical.

  1. 11. Structural and functional studies on ribonucleotide reductase protein B2 from Escherichia coli

    Författare :Margareta Karlsson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Ribonucleotide reductases; Eshcerichia coli;

    Sammanfattning : Ribonucleotide reductase catalyzes the reduction of ribonucleotidesto the corresponding deoxyribonucleotides, the building blocks forDNA. The enzyme from Escherichia coli consists of two proteins.Bl and B2. Protein B2 contains two dinuclear iron centers and astable tyrosyl radical. LÄS MER

  2. 12. Reaction Mechanism and Allosteric Regulation of Class Ia Ribonucleotide Reductase from Escherichia coli

    Författare :Alex Kasrayan; Britt-Marie Sjöberg; Bengt-Harald Jonsson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi;

    Sammanfattning : Ribonculeotide reductase (RNR) plays a key role in catalysing a reaction that provides all living organisms with building blocks for DNA. The RNR enzyme catalyses the conversion of ribonucleotides to their corresponding deoxyribonucleotides, by using free radical chemistry. LÄS MER

  3. 13. Ribonucleotide reductase and DNA damage

    Författare :Pelle Håkansson; Lars Thelander; Claes Gustafsson; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ribonucleotide reductase; DNA damage; dNTP pools; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : A prerequisite for a multicellular organism to survive is the ability to correctly replicate and repair DNA while minimizing the number of heritable mutations. To achieve this, cells need a balanced supply of deoxyribonucleoside triphosphates (dNTPs), the precursors for DNA synthesis. LÄS MER

  4. 14. EPR Studies of Ruthenium-Manganese Complexes as Biomimetic Models for Photosystem II - Approaching Artificial Photosynthesis

    Författare :Ping Huang; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; WOC; bridging-mode modification; water oxidation; EPR; Ru-Mn complexes; PSII; Artificial Photosynthesis; D donor -S sensitizer -A acceptor molecular module; High Mn valence states.; Biochemistry; Metabolism; Biokemi; metabolism;

    Sammanfattning : In natural photosynthesis, solar energy is converted to chemical energy by photosynthetic reaction centers. In green plants and algae, Photosystem II (PSII) and Photosystem I (PSI) absorb light and utilize the charge separation reactions to convert solar energy to chemical energy. LÄS MER

  5. 15. Herpes simplex ribonucleotide reductase

    Författare :Rolf Ingemarson; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; NATURVETENSKAP; TEKNIK OCH TEKNOLOGIER; NATURAL SCIENCES; ENGINEERING AND TECHNOLOGY; Ribonucleotide reductase; herpes simplex virus;

    Sammanfattning : In all bacterial, plant and animal cells, as well as in many viruses, genetic information resides in DNA (deoxyribonucleic acid). Replication of DNA is essential for proliferation, and DNA-containing viruses (such as herpesviruses) must carry out this process within the mammalian cells they infect. LÄS MER