Sökning: "tyrosine hydroxylase"

Visar resultat 16 - 20 av 72 avhandlingar innehållade orden tyrosine hydroxylase.

  1. 16. Experimental Studies of BMP Signalling in Neuronal Cells

    Författare :Susanna Althini; Ted Ebendal; Carl-Henrik Heldin; Ingrid Strömberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Bone Morphogenetic Protein BMP ; Growth Differentiation Factor 10 GDF10 ; Aktivne-receptor Like Kinase 2 ALK2 ; Tyrosine Hydroxylase TH ; Neurotrophic Factor; Neurite Outgrowth; Hippocampus; Catecholamine; PC12; Sympathetic Ganglia; Substantia Nigra SN ; Gene Targeting; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; Medicinsk utvecklings- och neurobiologi;

    Sammanfattning : The developing nervous system depends largely on extracellular cues to shape its complex network of neurons. Classically, neurotrophins are known to be important mediators in this process. LÄS MER

  3. 17. Neuroblastoma incidence, biology and outcome : with special emphasis on quantitative analysis of tyrosine hydroxylase mRNA in blood and bone marrow

    Författare :Catarina Träger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neuroblastoma, the most common malignant disease of early childhood, accounts for 6% of childhood malignancies but is responsible for 9% of paediatric cancer related deaths. The tumour originates from cells in the neural crest and has a very heterogeneous clinical course. LÄS MER

  4. 18. The functional role of the lateral olivocochlear system and mechanisms underlying sound condtioning

    Författare :Xianzhi Niu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cochlea; dopamine; tyrosine hydroxylase; sound conditioning; apoptosis; acoustic trauma; lateral olivocochlear nucleus; D1 receptor; efferents;

    Sammanfattning : Sound conditioning is a process induced by a low-level, non-damaging acoustic stimulus that provides protection against subsequent detrimental forms of acoustic trauma. Many hypotheses have been advanced to explain the effect of sound conditioning, but the mechanisms underlying this phenomenon are still not yet known. LÄS MER

  5. 19. Genetic aspects on schizophrenia and cerebrospinal fluid monoamine metabolites : focus on association studies with candidate genes

    Författare :Erik Jönsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :association study; schizophrenia; DNA polymorphisms; dopamine receptors DRD2; DRD3; DRD4 ; tyrosine hydroxylase; tryptophan hydroxylase; catechol-O-methyltransferase; neurotrophin-3; ciliary neurotrophic factor; healthy subjects; cerebrospinal fluid;

    Sammanfattning : Schizophrenia is a syndrome with psychotic symptoms. The pathogenesis of schizophrenia most likely reflects brain abnormalities and heritable components are present. The principal objective of the present thesis was to investigate some possible genetic influences in the genesis or pathophysiology of schizophrenia. LÄS MER

  7. 20. Genes that modulate or mediate dopaminergic neurotransmission : expression of the human prodynorphin gene and association studies with candidate genes in an alcohol patient sample

    Författare :Thomas Geijer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :association study; alcoholism; DNA polymorphisms; dopamine receptors DRD2; DRD3; DRD4 ; tyrosine hydroxylase TH ; prodynorphin; messengerRNA; gene expression; promotor Stockholm 1997;

    Sammanfattning : The development of alcoholism may at least partly be attributed to the effect of ethanol on reward and reinforcement. As a genetic influence in the vulnerability to alcoholism and drug abuse has been documented, it is of interest to investigate genes active in brain structures which mediate reward and reinforcement. LÄS MER