Sökning: "type 2 diabetes mellitus"

Visar resultat 11 - 15 av 281 avhandlingar innehållade orden type 2 diabetes mellitus.

1. 11. Gestational Diabetes Mellitus - Diagnostic Implications During Pregnancy and Follow-Up

   Författare :Rickard Claesson; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gestational diabetes mellitus GDM ; Oral glucose tolerance test; Type-2 diabetes; Diagnostic criteria; HbA1c; Screening test; Follow-up; Body mass index BMI ; Glucose levels; Large for gestational age LGA ; Seasonal variation;

   Sammanfattning : .... LÄS MER

3. 12. Genetic and Metabolic Markers for the Development of Diabetes after Gestational Diabetes Mellitus

   Författare :Magnus Ekelund; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral glucose tolerance tests; Genetics; Autoimmunity; Insulin sensitivity; Gestational diabetes mellitus; Insulin secretion; HbA1c; Fasting glucose; FTO-gene; Postpartum diabetes;

   Sammanfattning : The aims of this work were to determine the prevalence of postpartum diabetes among women with gestational diabetes mellitus (GDM) in a prospective study 5 years postpartum; to characterize these women according to insulin secretion, insulin sensitivity, autoimmunity and genetics; and to identify possible markers and predictors for the development of manifest diabetes. The subjects were recruited through a regional screening programme in which oral glucose tolerance tests (OGTTs) are routinely offered to all pregnant women. LÄS MER

4. 13. Dissecting the role of micro-RNAs in diabetes

   Författare :Caroline Bolmeson; Create Health; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Type 2 diabetes; micro-RNA; Dicer; beta-cell function; insulin secretion; glucose; NOD mouse; Goto-Kakizaki rat; human islets; thymocytes; apoptosis;

   Sammanfattning : The role of miRNAs in pancreatic islets and β-cell function and in the development of diabetes in human and rodents have been investigated in this thesis. Dicer1 was specifically deleted in vivo in pancreatic β-cells under the RIP-promoter in mice. LÄS MER

5. 14. Fibrinolytic factors in relation to anthropometry and incident type 2 diabetes

   Författare :Jenny Hernestål Boman; Lars Johansson; Jan-Håkan Jansson; Tomas Lindahl; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; folkhälsa; Public health; cardiovascular disease; hjärt- och kärlforskning;

   Sammanfattning : Fibrinolytic imbalance is associated with cardiovascular disease and its risk factors. The longitudinal changes in the fibrinolytic factors tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1) and tPA/PAI-1 complex have been inadequately studied in the general population and in relation to incident type 2 diabetes mellitus (T2DM). LÄS MER

7. 15. Obesity in diabetes. Cardiovascular outcomes and risk factor trajectories

   Författare :Jon Edqvist; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 diabetes mellitus; type 2 diabetes mellitus; body mass index; cardiovascular disease; epidemiology; reverse causality; mortality; heart failure; myocardial infarction; trajectories; machine learning;

   Sammanfattning : Introduction: The association between body mass index (BMI) and mortality in diabetes is complex and sparsely investigated for cardiovascular (CVD) outcomes. We aimed to investigate these relationships among patients with type 1 and type 2 diabetes using data from the Swedish national diabetes registry (NDR), with focus on potential reverse causality. LÄS MER