Sökning: "two-dimensional gel electrophoresis"

Visar resultat 11 - 15 av 65 avhandlingar innehållade orden two-dimensional gel electrophoresis.

1. 11. Self-assembly Strategies for Functional DNA Nanostructures

   Författare :John Tumpane; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbon nanotube; polarised spectroscopy; nanotechnology; self-assembly; orientation; lipid membrane; gel electrophoresis; DNA;

   Sammanfattning : The technological revolution of the twentieth century was famously subject to Moore’s law which related the rate of growth to the ability to scale-down the size of the components – size matters. Several decades later we are, however, approaching the limit of what is possible with silicon wafers. LÄS MER

3. 12. Electrifying the Molecules of Life : Peptide and Protein Analysis by Capillary Electrophoresis Coupled to Electrospray Ionization Mass Spectrometry

   Författare :Magnus Wetterhall; Jonas Bergquist; Karin E. Markides; Dominic M. Desiderio; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Capillary electrophoresis CE ; Electrospray ionization ESI ; Mass spectrometry MS ; Peptides; Proteins; Cerebrospinal fluid CSF ; Graphite coating; Monomer coating; Polymer coating; Analytisk kemi; Analytical chemistry; Analytisk kemi;

   Sammanfattning : This thesis describes the current status and novel aspects of the analysis of the molecules of life, i.e. peptides and proteins, using capillary electrophoresis (CE) coupled to mass spectrometry (MS) via (sheathless) electrospray ionization (ESI). Early reports of sheathless CE-ESI-MS were plagued by limited lifetimes of the electrospray emitter. LÄS MER

4. 13. Cancer proteomics : characterisation of protein expression in human epithelial tumours

   Författare :Ayodele A Alaiya; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Two-dimensional gel electrophoresis; protein expression; mass spectrometry; epithelial tumour; heterogeneity;

   Sammanfattning : Defining differences in protein expression between tumour cells of various degrees of malignancy is a first step in the development of markers for tumour diagnosis. In this thesis, the expression of multiple proteins in benign and malignant human ovarian, breast and prostate tumours was examined using two-dimensional gel electrophoresis (2-DE). LÄS MER

5. 14. Protein expression in prostate cancer

   Författare :Helena Lexander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Two-dimensional gel electrophoresis; protein expression; biomarker; Gleason grade; DNA-ploidy;

   Sammanfattning : The molecular pathology of prostate cancer (PCa) is complex and the pathways and the acquired molecular defects responsible for PCa initiation, development and progression are still largely unknown. Tumors of the prostate have an unpredictable behavior and in clinically detected cancers it is presently not possible to assess tumor aggressiveness. LÄS MER

7. 15. The Bronchoalveolar Lavage Proteome- Phenotypic associations to smoking and divergence towards development of COPD

   Författare :Amelie Plymoth; allergologi och palliativ medicin Lungmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; mass spectrometry; proteomics; 2-D gel; COPD; bronchoalveolar lavage;

   Sammanfattning : Proteomic analysis of bronchoalveolar lavage (BAL) fluid from smokers at risk of developing chronic obstructive pulmonary disease (COPD) and never smokers is described. COPD is currently the world's fourth leading cause of death and its prevalence is increasing. LÄS MER