Sökning: "turnover model"

Visar resultat 1 - 5 av 169 avhandlingar innehållade orden turnover model.

1. 1. Modelling of drug-effect on time-varying biomarkers

   Författare :Felix Held; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cortisol; TNFα; hierarchical modelling; turnover model; pharmacokinetic pharmacodynamic modelling; cortisol TNFα hierarchical modelling turnover model pharmacokinetic pharmacodynamic modelling;

   Sammanfattning : Model-based quantification of drug effect is an efficient tool during pre-clinical and clinical phases of drug trials. Mathematical modelling can lead to improved understanding of the underlying biological mechanisms, help in finding shortcomings of experimental design and suggest improvements, or be an effective tool in simulation-based analyses. LÄS MER

3. 2. Biogas generation in landfills : equilibria, rates & yields

   Författare :Mattias Åkesson; Avdelningen för Teknisk vattenresurslära; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; geographical and geological engineering; Hydrogeology; model; limitation; volatile fatty acids; kinetics; biogas; thermodynamics; methane; Landfill; test cell; Hydrogeologi; teknisk geologi; teknisk geografi; Geophysics; physical oceanography; meteorology; Geofysik; fysisk oceanografi; meteorologi;

   Sammanfattning : Landfilling in "cells" has become more common in recent years. Different waste streams are guided to different cells, among which the biocell is a landfill designed for biogas production. In this thesis, the dependence of biogas generation on waste composition was investigated. LÄS MER

4. 3. Pharmacodynamics of Enzyme Induction and its Consequences for Substrate Elimination

   Författare :Mats O. Magnusson; Rikard Sandström; Mats Karlsson; Ulf Bredberg; Uppsala universitet; []
   Nyckelord :Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Enzyme induction; Time course; Turnover model; Mechanism-based; Modelling; NONMEM; Farmakokinetik Farmakoterapi;

   Sammanfattning : Enzyme induction is a process whereby a molecule enhances the expression of enzymes. If the affected enzymes are involved in the elimination of a drug, this may result in a drug interaction. Induction is therefore of major concern during drug development and in clinical practice. LÄS MER

5. 4. Essays on Firm Turnover, Growth, and Investment Behavior in Ethiopian Manufacturing

   Författare :Mulu G Gebreeyesus; Göteborgs universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; firm turnover; productivity; firm growth; investment; adjustment cost; irreversibility; manufacturing; Africa; Ethiopia.;

   Sammanfattning : This thesis analyses the dynamics and investment behavior of Ethiopian manufacturing firms in post-reform period using establishment level industrial census panel data from 1996 to 2003. Three related topics such as firm turnover and productivity differentials, determinants of firm growth, and the effect of adjustment cost and irreversibility on firm investment decisions are investigated empirically. LÄS MER

7. 5. Studies on mRNA turnover in bacteria

   Författare :Martin Persson; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; aprE; GlpP; glpD; mRNA secondary structure; Bacillus subtilis; mRNA stability; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Genetic information, which is stored in DNA, is transferred to messenger RNA (mRNA) in a process called transcription. mRNAs are then translated by ribosomes into proteins which, with some important exceptions, catalyze chemical reactions in cells. Since cells must be able to adapt to changes in the environment, mRNAs must be unstable. LÄS MER