Sökning: "tumour control"

Visar resultat 6 - 10 av 195 avhandlingar innehållade orden tumour control.

  1. 6. Molecular and epigenetic control of CNS tumour and progenitor cells

    Författare :Aileen Gracias; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite advances in diagnosis and treatment, CNS tumours continue to result in high mortality and morbidity. Glioblastoma mutliforme (GBM), the most common primary brain tumour, is a recurrent tumour that despite advances in treatment, continues to demonstrate a median time of survival of 14.6 months. LÄS MER

  3. 7. Theoretical modelling of tumour oxygenation and influences on treatment outcome

    Författare :Iuliana Toma-Dasu; Mikael Karlsson; Svensson Hans; J F Fowler; Borivoj Vojnovic; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; Computer simulation; Electrode; Polarographic measurements; Tumour oxygenation; Hypoxia; Strålningsvetenskap; Radiation biology; Strålningsbiologi; radiofysik; radiation physics;

    Sammanfattning : One of the main problems in curing cancer resides in the different microenvironment existing in tumours compared to the normal tissues. The mechanisms of failure are different for radiotherapy and chemotherapy, but they all relate to the poor blood supply known to exist in tumours. LÄS MER

  4. 8. Gene expression and its physiological control in disease and development : Studies on the human PDGF-B gene and tumour hypoxia

    Författare :Erik Ullerås; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Zoologisk utvecklingsbiologi; Animal Development;

    Sammanfattning : Strict control of gene expression is essential during development and in response to physiological stimuli. This thesis describes the functional characterisation of the gene regulatory mechanisms controlling the expression of the potent human growth factor Platelet Derived Growth Factor B gene, in a cell type specific context and in response to low oxygen tension. LÄS MER

  5. 9. Interstitial laser thermotherapy (ILT) of breast cancer - Methodology and immunological responce

    Författare :Kristin Huld-Haraldsdottir; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Laser thermotherapy; Minimally invasive treatment; Tumour immunology; Thermal treatment; Tumour size; Magnetic resonance imaging;

    Sammanfattning : Interstitial laser thermotherapy (ILT) is an attractive form of local therapy against cancer because of its anti-tumor immune activity. The aim of this work was to evaluate ILT in breast cancer with respect to technique, changes in tissue immunocompetent cells and effect on prognosis. LÄS MER

  7. 10. Regulation of apoptosis during treatment and resistance development in tumour cells

    Författare :Jeanette Blomberg; Erik Lundgren; John Eriksson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumörbiologi; Tumour biology; Tumörbiologi;

    Sammanfattning : Induction of apoptosis is the most studied cell death process and it is a tightly regulated physiological event that enables elimination of damaged and unwanted cells. Apoptosis can be induced via activation of either the intrinsic or the extrinsic signalling pathway. LÄS MER