Sökning: "tumorsuppressor"

Hittade 2 avhandlingar innehållade ordet tumorsuppressor.

1. 1. Phospholipase C β3, and its role in endocrine tumorigenesis

   Författare :Peter Stålberg; Uppsala universitet; []
   Nyckelord :Medical sciences; Phospholipase C beta 3; endocrine tumors; in situ hybridization; transfection; tumorsuppressor; differential expression; gene targeting; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : The Phospholipase C β3 (PLCB3) gene is located on chromosome 11q13, in the vicinity of theMultiple Endocrine Neoplasia type 1 (MEN1) suppressor gene. PLCB3 has been implicated inendocrine tumorigenesis based on findings of low expression in endocrine tumors, and the probableexistence of other suppressor genes located at 11q13. LÄS MER

3. 2. Keratinocyte differentiation. Involvement of the growth hormon (GH)/insulinlike growth factor1 (IGFI) axis and IGF1 post receptor signaling

   Författare :Elisabeth Björntorp Mark; Göteborgs universitet; []
   Nyckelord :IGF1R; GH; Id1; keratinocytes; psoriasis;

   Sammanfattning : At cellular level, little is known about the genes that regulate keratinocyte differentiation andproliferation. Psoriasis is regarded as a T-cell mediated inflammatory disease with hyperproliferativekeratinocytes. LÄS MER