Sökning: "tumor-infiltrating lymphocytes"
Visar resultat 1 - 5 av 35 avhandlingar innehållade orden tumor-infiltrating lymphocytes.
1. Immuno Gene Therapy of Rat Brain Tumors with interferon-gamma transfected glioma cells
Sammanfattning : Immunotherapy is a new promising approach in cancer treatment. In the future, it will hopefully offer an alternative to existing brain tumors treatments, which are unable to cure. We have established an experimental, low immunogenic, brain tumor model in the rat. LÄS MER
2. Novel immunotherapies for metastatic melanoma - from mouse models towards clinical trials
Sammanfattning : Immunotherapies including checkpoint blockade and adoptive T cell transfer (ACT) show great promise for the treatment of melanoma, with long-term effects in some patients. However, around half of the patients with metastatic malignant melanoma will not be cured with available therapies today, and these patients require other treatment strategies. LÄS MER
3. The use of immunological biomarkers to improve individualization of postoperative radiotherapy in breast cancer
Sammanfattning : Radiotherapy (RT) forms the cornerstone of most curative breast cancer treatment due to its well-established risk-reducing effect on local recurrences at the population level. However, there is heterogeneity regarding treatment benefits at the individual level, and research currently aims to better tailor treatment decisions based on tumor biology. LÄS MER
4. Inflammatory Cells and Mediators in the Tumor Microenvironment of Breast Cancer
Sammanfattning : .... LÄS MER
5. Tumor-infiltrating lymphocytes and the PD-L1/PD-1 signaling axis in breast cancer : biology and clinical implications
Sammanfattning : Cancer immunotherapy and especially immune checkpoint blockade therapy has revolutionized cancer treatment in many tumor types including breast cancer (BC). The expression and specific role of Programmed Death-1 (PD-1)/Programmed Death-Ligand 1 (PD-L1) signaling axis, immune-related gene signatures and immune cell subpopulations needs to be fully elucidated while the identification of prognostic and predictive biomarkers in BC is of utmost importance. LÄS MER