Sökning: "tumor microenvironment"

Visar resultat 21 - 25 av 195 avhandlingar innehållade orden tumor microenvironment.

  1. 21. Mutation and immune profiling of non-small cell lung cancer

    Författare :Linnéa La Fleur; Johan Botling; Fernando López-Ríos; Uppsala universitet; []
    Nyckelord :Non-small cell lung cancer; Tumor microenvironment; Tumor-associated macrophages; Immune infiltrates; PD-L1; Mutation patterns; Immune therapy; MARCO; TP53; STK11; KRAS;

    Sammanfattning : Several novel therapies that target molecular alterations and immune checkpoints in lung cancer have been introduced in the last decade. Still, only a minority of patients obtain long term disease control and overall survival remains poor. LÄS MER

  3. 22. Dissection of the tonsillar cancer immune microenvironment : Perspectives of the myeloid APC – T-cell axis

    Författare :David Gomez Jimenez; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic cell; Macrophage; CD8 T-cell; Human papillomavirus HPV ; Tonsillar cancer; Tumor microenvironment; Immuno-oncology; Single-cell RNA sequencing; Spatial proteomics; Flow Cytometry;

    Sammanfattning : Tonsillar cancer (TC) is a subset of head and neck cancer (HNC). TC incidence is sharply rising due to an increased prevalence of human papillomavirus (HPV) infection in the western world. Currently HPV status is considered during clinical staging due to its positive association to patient prognosis. LÄS MER

  4. 23. The tumor immune microenvironment and clinical outcome in patients with esophageal and gastric adenocarcinoma

    Författare :Maria C Svensson; Personlig patologi och cancerbehandling; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin och hälsovetenskap; tumor immune microenironment; Esophageal cancer; Gastric cancer; prognosis; Prediction; Adenocarcinoma; T cells; B cells; NK cells; tumor-associated macrophage TAM ; PD-L1; PD-1;

    Sammanfattning : .... LÄS MER

  5. 24. Exploring the functional heterogeneity of the tumor microenvironment

    Författare :Eliane Cortez; Avdelningen för translationell cancerforskning; []
    Nyckelord :;

    Sammanfattning : Tumors are complex entities, composed of different functional populations of malignant and stromal cells. There is an emerging importance to understand previously unmapped communication routes between different cell and non-cell compartments of the tumor microenvironment. LÄS MER

  7. 25. Tumor microenvironment derived biomarkers in renal cell cancer

    Författare :Magnus Frödin-Bolling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Renal cell carcinoma (RCC) is the 13th most common malignancy worldwide, and constitutes around 2% of all malignant tumors. The entity renal cell carcinoma comprises a heterogenous group of malignant tumors that originates from the epithelial cells in the renal proximal tubule. LÄS MER