Sökning: "tumor immunotherapy"

Visar resultat 21 - 25 av 153 avhandlingar innehållade orden tumor immunotherapy.

  1. 21. Immunological aspects of intratumoral chemotherapy and immunotherapy in malignant brain tumors

    Författare :Julio Enriquez Perez; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma GBM ; Immunotherapy; Mouse glioma; Convection-enhanced delivery; Intratumoral chemotherapy; Glioblastom; Immuneterapi;

    Sammanfattning : Advances in surgery, chemo- and radiotherapy have only modestly improved survival rates of malignant brain tumor patients during the last decades. Emerging evidence suggests that an efficient treatment of malignant brain tumors will likely require the management of multiple aspects of tumor pathobiology in order to manipulate features as tumor heterogeneity and tumor immunosuppression. LÄS MER

  3. 22. Interaction studies of idiotypic and antiidiotypic antibodies at experimental tumor targeting

    Författare :Ann Erlandsson; Mats Ohlin; Umeå universitet; []
    Nyckelord :anti-idiotypic antibody; clearing; cytokeratin 8; epitope; idiotypic antibody; immunotherapy;

    Sammanfattning : An increasing number of antibodies are being labeled with radionuclides for immunotargeting, but the negative side effects generated on normal tissues by the nuclide remains a significant problem. The clearing of non-tumor-targeted radiolabeled antibodies from the circulation contributes significantly to improved targeting; it has been demonstrated that anti-idiotypic antibodies can be used for this purpose. LÄS MER

  4. 23. Synergistic effects of mesenchymal stromal cells and immunotherapy in experimental brain tumors

    Författare :Salina Gunnarsson; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stromal cells; rat; IFNγ; IL-7; immunotherapy; glioma;

    Sammanfattning : Glioblastoma multiforme (GBM) is the most common and aggressive form of primary brain tumor. In spite of surgical resection, combined radiation therapy and chemotherapy, the mean survival is less than 15 months following diagnosis. LÄS MER

  5. 24. Translational and clinical aspects of pancreatic cancer

    Författare :Caroline Vilhav; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; circulating tumor cells; extracellular vesicles; immunotherapy; PDX model; pancreaticoduodenectomy; postoperative complications; postpancreatectomy hemorrhage;

    Sammanfattning : Pancreatic cancer is a disease with dismal prognosis due to late detection and ineffective treatments. The majority of the patients already have disseminated disease at the time of diagnosis. The only potential curative treatment, surgery, is extensive with high morbidity and non-ignorable mortality. LÄS MER

  7. 25. Experimental models of pediatric brain tumors. Establishment, immunophenotyping and clinical implications

    Författare :Emma Sandén; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric Brain Tumor; Experimental model; Immunotherapy; Immune monitoring; Medulloblastoma;

    Sammanfattning : Brain tumors are the most common solid tumors in children. Current treatment protocols fail in 25% of patients and are associated with significant long-term adverse effects in survivors. LÄS MER