Sökning: "tumor antigens"

Visar resultat 1 - 5 av 111 avhandlingar innehållade orden tumor antigens.

  1. 1. Activity of tumor-antigens in polyomavirus replication

    Författare :Hongyun Li; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Tumor-Antigens; DNA Replication; Cell-cycle; Phosphorylation; J-domain; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Polyomavirus replication needs an active cell environment, and the viral DNA replication is cell cycle regulated. Tumor antigens (T-antigens) of mouse polyomavirus, especially large T-antigen, are necessary for the replication. LÄS MER

  3. 2. Development of a Cancer Vaccine Targeting Tumor Blood Vessels

    Författare :Elisabeth J. M Huijbers; Anna-Karin Olsson; Arjan W. Griffioen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vaccine; Therapeutic; Cancer; Tumor; Angiogenesis; Immunization; Vascular; Extracellular matrix; Biomedicinsk laboratorievetenskap; Biomedical Laboratory Science; Medical Cell Biology; Medicinsk cellbiologi; Oncology; Onkologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue.In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. LÄS MER

  4. 3. Expression of Tissue Antigens in Human Pluripotent Stem Cells and Alterations During Differentiation : Potential application in regenerative medicine for treatment of terminal cell and organ failure

    Författare :Karin Säljö; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pluripotent stem cells; Differentiation; Histo-blood group antigens; HLA; Tissue antigens; Sialyl-lactotetra; Cell surface antigens; Transplantation; Regenerative medicine;

    Sammanfattning : The major limiting factor in the treatment of patients with end-stage organ failure is the insufficient number of human organs available for transplantation. An unlimited access to human cells, tissues and organs would also open up possibilities to treat several chronic diseases, such as diabetes, neurological and cardiovascular diseases, affecting millions of patients worldwide. LÄS MER

  5. 4. Transcriptomic and Proteomic Analysis of Tumor Markers in Tissue and Blood from Patients with Lung Cancer

    Författare :Dijana Djureinovic; Patrick Micke; Keith Kerr; Uppsala universitet; []
    Nyckelord :non-small cell lung cancer; prognostic biomarkers; cancer-testis antigens; prediction model; tumor markers; autoantibodies; testis; screening; Patologi; Pathology;

    Sammanfattning : Despite recent treatment advancements, the survival outcome remains poor for the majority of patients with non-small cell lung cancer (NSCLC). The aim of this thesis was to evaluate protein expression to predict prognosis and identify biomarkers that can be used as targets for immunotherapy or for early detection of NSCLC. LÄS MER

  7. 5. Discovery of targets for tumor immunotherapy using phage display technology

    Författare :Jesper Tordsson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; colon cancer; melanoma; tumor immunotherapy; phage display; scFv; Immunologi; serologi; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : This thesis has focused on the development of methods and their applications for the identification of antibodies reactive with tumor associated antigens (TAA). The phage display technology provides a powerful mean to generate antibodies potentially useful for tumor immunotherapy. LÄS MER