Sökning: "tumör reduktion"

Hittade 3 avhandlingar innehållade orden tumör reduktion.

  1. 1. Hepatic and Peritoneal Colorectal Metastases : Aspects of Prognosis and Treatment

    Författare :Haile Mahteme; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Colorectal cancer; lever metastas; peritoneal metastas; intraperitoneal; tumör reduktion; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Although two-thirds of colorectal cancer patients are cured by surgery, approximately 50% of the patients with this disease develop locally recurrent or distant metastases during the course of their illness. The aim of this study was to identify metastatic sites associated with poor prognosis in rectal cancer and then to investigate methods that can prevent the development and growth of metastases and optimise uptake of drugs at these sites in animal models. LÄS MER

  3. 2. Magnetic bead-based isolation of biological therapeutic modalities

    Författare :Nils A. Brechmann; Véronique Chotteau; Nigel Titchener-Hooker; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic bead separation; Magnetic beads; Protein A; Protein G; Negative cell isolation; Monoclonal antibody; induced pluripotent stem cells; human mesenchymal stem cells; Allogenic cell therapy; Biomanufacturing; cell clarification; Biotechnology; Bioteknologi;

    Sammanfattning : Biopharmaceutical modalities, such as monoclonal antibodies or the less established cell therapies, are nowadays very important for the treatment of severe or incurable diseases. The manufacturing of such modalities is complex and costly, including the downstream processing, which is highly essential to ensure the safety and quality of the product. LÄS MER

  4. 3. The mechanism of HAMLET-induced cell death - cellular signalling, oncogenes and clinical perspectives

    Författare :Petter Storm; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HAMLET; cancer; cell death; c-Myc; glycolysis; hexokinase; ion channels; p38 MAPK; lipids; colon cancer; beta-catenin;

    Sammanfattning : Despite recent advances in cancer treatment, truly innovative approaches are required to move beyond the modest benefits achieved to date. HAMLET is a human protein-lipid complex originally discovered in breast milk able to kill a wide range of tumour cells while leaving healthy, differentiated cells unaffected. LÄS MER