Sökning: "tucaresol"

Hittade 3 avhandlingar innehållade ordet tucaresol.

  1. 1. Immune and gene therapies for cancer and infectious diseases

    Författare :Jehad Charo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Immunotherapy; gene therapy; cytokines; MHC-1; tucaresol; EBV; mycobacteria; HER-2; Tumors;

    Sammanfattning : Annually more than 20 million deaths are globally caused because of infections or cancer. This accounts for 41.5% of annual deaths. New techniques are supposed to constitute our tools in the fight against these types of deaths. LÄS MER

  3. 2. Vaccine strategies based on mycobacterial heat shock protein 65

    Författare :Maria Sundbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mycobacteria; DNA vaccination; Hsp65; T cells; CD8 T cell epitopes;

    Sammanfattning : Mycobacteria can infect macrophages and dendritic cells (DC), where they reside inside the endosomal compartment. The importance of CD4+ T cells in protective immunity against mycobacteria and other intracellular pathogens is well established, and for a long time these cells were thought to be the major defense in controlling an infection. LÄS MER

  4. 3. Enhancing T cell mediated immunity in DNA vaccination

    Författare :Jan Alvar Lindencrona; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA vaccination; CTL; T cell; IFN-gamma; anti-tumor immunity; HER-2 neu; Influenza; LCMV; Virus-Like Particles; murine models; adjuvants; immunotherapy;

    Sammanfattning : For centuries infectious diseases have been one of the main causes of death in the world. With the invention of vaccine technology 200 years ago, we have been able to impede and even eradicate several dangerous pathogens. LÄS MER