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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Epidemiological aspects of tuberculosis in Guinea-Bissau, West Africa

    Författare :Per Gustafson; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tuberculin skin test; Infections; Infektioner; survival; mortality; case fatality rate; risk factor; incidence; Guinea-Bissau; Africa; epidemiology; Mycobacterium tuberculosis; HIV-2; HIV-1; HIV; Tbc; Tuberculosis; TB;

    Sammanfattning : Tuberculosis (TB) has plagued the humanity for several thousands of years. The bacteria causing TB is mainly spread from person to person as an aerosol transmission. It is estimated that one third of the world’s population is infected with the disease; about 10% of these will develop active TB during their lifetime. LÄS MER

  3. 2. Dynamics of tuberculosis infection in Sweden

    Författare :Niclas Winqvist; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tuberculosis; latent tuberculosis infection; long-term follow-up; Øresund region; interferon-gamma release assay; tuberculin skin test;

    Sammanfattning : Sweden provides a special setting for epidemiological and demographic studies of tuberculosis (TB) infection over time for principally two reasons; first, the Swedish TB epidemic has undergone a tremendous transition since the end of the 19th century, when TB was highly endemic, to the current situation with practically interrupted indigenous transmission since several decades. Second, an increasing proportion of persons who grew up before TB transmission virtually disappeared in the 1960s are reaching advanced age, and thus creating conditions that predispose to reactivation of latent TB infection (LTBI). LÄS MER

  4. 3. BCG vaccination and the tuberculin skin test in a country with low prevalence of tuberculosis. Epidemiological and immunological studies in healthy subjects

    Författare :Harald Fjällbrant; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 4. Studies of human dendritic cells in the skin after antigen exposure

    Författare :Emily Bond; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Dendritic cells (DCs) act at the interface of innate and adaptive immunity. They are capable of inducing strong effector immune responses to invading pathogens, but also exert important functions in the maintenance of tolerance. LÄS MER

  7. 5. Innate immune responses in vivo after antigen administration : implications for vaccine development

    Författare :Frank Liang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inducing high magnitude of antibodies with epitope breadth over prolonged periods of time is likely a prerequisite to prevent several of the world’s most serious infectious diseases such as HIV-1, malaria and tuberculosis for which there are no vaccines yet. A much better understanding of the innate immune mechanisms that are critical for inducing strong responses to vaccination is therefore essential. LÄS MER