Sökning: "tryptophan"

Visar resultat 1 - 5 av 145 avhandlingar innehållade ordet tryptophan.

  1. 1. Tryptophan photoproducts : regulation of CYP1A1 transcription and modulation of cell growth

    Författare :Yu-Dan Wei; Dieter Schrenk; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; toxikologisk genetik; Genetic Toxicology;

    Sammanfattning : The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in the regulation of many drug-metabolizing enzymes. The regulation of cytochrome P4501A1 (CYP1A1) has been most intensively studied. LÄS MER

  2. 2. Tryptophan-related Neurotransmission in the Brain: Disturbances Associated with Experimental Hepatic Encephalopathy

    Författare :Peter B F Bergqvist; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tetrodotoxin; serotonin; release; rat; quinolinic acid; potassium; chloroamphetamine; noradrenaline; neurotransmission; microdialysis; hepatic encephalopathy; fenfluramine; drug safety; dopamine; coma; citalopram; ammonia; calcium; brain; tryptophan; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : In the present study, L-tryptophan (TRP)-related disturbances in the brain in experimental hepatic encephalopathy (HE) were investigated. The endogenous NMDA-receptor agonist and L-TRP metabolite quinolinic acid (QUIN) has been suggested to be involved in the pathogenesis of HE. LÄS MER

  3. 3. Functional characterization of tyrosine and tryptophan transport in fibroblasts from healthy controls, patients with schizophrenia and bipolar disorder

    Författare :Ravi Vumma; Nikolaos Venizelos; Tommy Lewander; Dimitrios Kyriakidis; Örebro universitet; []
    Nyckelord :Fibroblasts; Tyrosine; Tryptophan; LAT1; Schizophrenia; Bipolar disorder; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Sammanfattning : .... LÄS MER

  4. 4. Amino acid transport and receptor binding properties in neuropsychiatric disorders using the fibroblast cell model

    Författare :Jessica Johansson; Nikolaos Venizelos; Lars Oreland; Örebro universitet; []
    Nyckelord :Fibroblasts; Bipolar disorder; ADHD; Tyrosine; Tryptophan; Alanine; Transport; mAChRs; Biomedicin; Biomedicine;

    Sammanfattning : Altered transport of the catecholamines and serotonin precursor amino acids tyrosine and tryptophan, might be one explanation for the dysfunctional neurotransmission implicated in the pathophysiology of bipolar disorder and Attention Deficit/Hyperactivity Disorder (ADHD). In previous studies, an altered amino acid transport has been found in schizophrenia and autism, when using the fibroblast cell model. LÄS MER

  5. 5. Peptide-tagged proteins in aqueous two-phase systems

    Författare :Anna Nilsson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; green fluorescent protein; cutinase; tryptophan; Aqueous two-phase system; peptide-tagged protein;

    Sammanfattning : This thesis deals with proteins containing peptide tags for improved partitioning in aqueous two-phase systems. Qualitatively the peptide-tagged protein partitioning could be predicted from peptide data, i.e. partitioning trends found for peptides were also found for the peptide-tagged proteins. LÄS MER