Sökning: "tryptophan"

Visar resultat 1 - 5 av 153 avhandlingar innehållade ordet tryptophan.

  1. 1. Tryptophan photoproducts : regulation of CYP1A1 transcription and modulation of cell growth

    Författare :Yu-Dan Wei; Dieter Schrenk; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; toxikologisk genetik; Genetic Toxicology;

    Sammanfattning : The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in the regulation of many drug-metabolizing enzymes. The regulation of cytochrome P4501A1 (CYP1A1) has been most intensively studied. LÄS MER

  3. 2. Tryptophan-related Neurotransmission in the Brain: Disturbances Associated with Experimental Hepatic Encephalopathy

    Författare :Peter B F Bergqvist; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tetrodotoxin; serotonin; release; rat; quinolinic acid; potassium; chloroamphetamine; noradrenaline; neurotransmission; microdialysis; hepatic encephalopathy; fenfluramine; drug safety; dopamine; coma; citalopram; ammonia; calcium; brain; tryptophan; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : In the present study, L-tryptophan (TRP)-related disturbances in the brain in experimental hepatic encephalopathy (HE) were investigated. The endogenous NMDA-receptor agonist and L-TRP metabolite quinolinic acid (QUIN) has been suggested to be involved in the pathogenesis of HE. LÄS MER

  4. 3. Mechanistic Studies on Proton-Coupled Electron Transfer from Tyrosine and Tryptophan Derivatives

    Författare :Astrid Nilsen-Moe; Leif Hammarström; Pia Ädelroth; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proton-Coupled Electron Transfer; PCET; Tyrosine; Tryptophan; Amino Acid Radicals; Transient Absorption; Chemistry with specialization in Physical Chemistry; Kemi med inriktning mot fysikalisk kemi;

    Sammanfattning : Proton-coupled electron transfer (PCET) from tyrosine (Y) and tryptophan (W) is vital to many redox reactions in Nature where PCET between several Ys, or Ws, or between a mix of Ys and Ws can be used to transfer electrons, or protons, or both over large distances of several Å. Studying the PCET reaction mechanisms of Y and W is important for fundamental knowledge, and can help researchers that wish to mimic redox reactions in Nature. LÄS MER

  5. 4. Functional characterization of tyrosine and tryptophan transport in fibroblasts from healthy controls, patients with schizophrenia and bipolar disorder

    Författare :Ravi Vumma; Nikolaos Venizelos; Tommy Lewander; Dimitrios Kyriakidis; Örebro universitet; []
    Nyckelord :Fibroblasts; Tyrosine; Tryptophan; LAT1; Schizophrenia; Bipolar disorder; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Sammanfattning : .... LÄS MER

  7. 5. Non-invasive monitoring of low molecular weight biomarkers relevant to skin inflammation and cancer

    Författare :Skaidre Jankovskaja; Tautgirdas Ruzgas; Johan Engblom; György Marko-Varga; Melinda Rezeli; Pawel Lukasz Urban; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tryptophan; Kynurenine; Phenylalanine; Tyrosine; Low molecular Weight Biomarkers; Non-Invasive; Skin Surface Sampling; Skin Permeability; Hydrogels; Prussian White; Health and society; Hälsa och samhälle;

    Sammanfattning : Development of skin inflammation and cancer in viable epidermis and dermis involve slow molecular weight (LMW) metabolites. We hypothesize that these LMW compounds can be collected on the surface of the skin and used for non-invasive diagnostics of skin disorders. LÄS MER