Sökning: "trkB"

Visar resultat 21 - 25 av 30 avhandlingar innehållade ordet trkB.

  1. 21. The effects of neurotrophic substances on primary sensory neurons following peripheral nerve injury

    Författare :Petri Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DRG; dorsal horn; NGF; BDNF; NT-3; substance P; calcitonin gene-related peptide; fluoride-resistant acid phosphatase; carbonic anhydrase; microglia; astroglia;

    Sammanfattning : Sensory impulses from the periphery is transmitted by primary sensory neurons located in dorsal root and cranial nerve ganglia. The primary sensory neurons are phenotypically diverse with regard to their expression of various chemical components. LÄS MER

  3. 22. Wrist ligaments : innervation patterns and ligamento-muscular reflexes

    Författare :Elisabet Hagert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Wrist ligaments; mechanoreceptors; proprioception; sensorimotor functions; neuromuscular control; ligamento-muscular reflexes; immunohistochemistry;

    Sammanfattning : Objectives: The principal role of wrist stability is to facilitate the dexterous hand in a multitude of functions. To achieve joint stability, in general, a fine interaction of both static and dynamic elements is of essence. LÄS MER

  4. 23. Biochemical and biophysical aspects of molecular recognition and signalling by neurotrophins

    Författare :Leopold Luna Ilag; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neurotrophins are members of a family of structurally and functionally related neurotrophic factors that control the development and maintenance of the nervous system. There are currently 5 members which make up this family: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin-4(NT-4) and neurotrophin-6 (NT-6), which so far is only described in fish. LÄS MER

  5. 24. Exploring inter- and intra-heterogeneity in childhood neuroblastoma and pheochromocytoma

    Författare :Wenyu Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neuroblastoma is the most common extra-cranial solid tumor of the sympathoadrenal cell lineage, which is a unique pediatric malignancy with remarkable inter- and intra-tumoral heterogeneity. In infants, neuroblastoma can regress spontaneously without treatment, while in older patients, neuroblastoma can develop with lethal progression with less than a 50% survival rate. LÄS MER

  7. 25. Effects of excess glucocorticoids on neural cell fate : long lasting consequences of adverse prenatal factors

    Författare :Mirko Conti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The developing nervous system is particularly vulnerable to high level of glucocorticoids (GCs). Excess GCs is often associated with decreased birth weight in relation to gestational age, and to increased risk of psychiatric disorders, like depression, later in life. LÄS MER